node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dred_0783 | Dred_1146 | Dred_0783 | Dred_1146 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | 0.945 |
Dred_0783 | Dred_1150 | Dred_0783 | Dred_1150 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | PFAM: Prephenate dehydrogenase; KEGG: mta:Moth_1333 prephenate dehydrogenase. | 0.984 |
Dred_0783 | Dred_1164 | Dred_0783 | Dred_1164 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | PFAM: amino acid-binding ACT domain protein; KEGG: dsy:DSY2247 hypothetical protein; Belongs to the UPF0735 family. | 0.933 |
Dred_0783 | aroA | Dred_0783 | Dred_1151 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.942 |
Dred_0783 | aroB | Dred_0783 | Dred_1021 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.813 |
Dred_0783 | aroC | Dred_0783 | Dred_1019 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.992 |
Dred_0783 | aroE | Dred_0783 | Dred_1018 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.813 |
Dred_0783 | aroK | Dred_0783 | Dred_0781 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.888 |
Dred_0783 | aroK-2 | Dred_0783 | Dred_1020 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.806 |
Dred_0783 | trpE | Dred_0783 | Dred_0248 | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.970 |
Dred_1146 | Dred_0783 | Dred_1146 | Dred_0783 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | 0.945 |
Dred_1146 | Dred_1150 | Dred_1146 | Dred_1150 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | PFAM: Prephenate dehydrogenase; KEGG: mta:Moth_1333 prephenate dehydrogenase. | 0.949 |
Dred_1146 | Dred_1164 | Dred_1146 | Dred_1164 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | PFAM: amino acid-binding ACT domain protein; KEGG: dsy:DSY2247 hypothetical protein; Belongs to the UPF0735 family. | 0.900 |
Dred_1146 | aroA | Dred_1146 | Dred_1151 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.472 |
Dred_1146 | aroB | Dred_1146 | Dred_1021 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.736 |
Dred_1146 | aroC | Dred_1146 | Dred_1019 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.964 |
Dred_1146 | trpE | Dred_1146 | Dred_0248 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.914 |
Dred_1150 | Dred_0783 | Dred_1150 | Dred_0783 | PFAM: Prephenate dehydrogenase; KEGG: mta:Moth_1333 prephenate dehydrogenase. | PFAM: prephenate dehydratase; Chorismate mutase; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | 0.984 |
Dred_1150 | Dred_1146 | Dred_1150 | Dred_1146 | PFAM: Prephenate dehydrogenase; KEGG: mta:Moth_1333 prephenate dehydrogenase. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | 0.949 |
Dred_1150 | Dred_1164 | Dred_1150 | Dred_1164 | PFAM: Prephenate dehydrogenase; KEGG: mta:Moth_1333 prephenate dehydrogenase. | PFAM: amino acid-binding ACT domain protein; KEGG: dsy:DSY2247 hypothetical protein; Belongs to the UPF0735 family. | 0.909 |