STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (314 aa)    
Predicted Functional Partners:
Dred_0381
PFAM: pyruvate kinase; PEP-utilising enzyme, mobile region; KEGG: chy:CHY_1144 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.976
Dred_2312
PFAM: pyruvate kinase; PEP-utilising enzyme, mobile region; KEGG: chy:CHY_1144 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.976
Dred_1064
TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; Conserved carboxylase region; KEGG: chy:CHY_1999 oxaloacetate decarboxylase, alpha subunit.
    
 0.961
Dred_2955
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: amino acid-binding ACT domain protein; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rxy:Rxyl_1110 malate dehydrogenase (oxaloacetate decarboxylating).
  
 0.956
Dred_0047
2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: chy:CHY_0043 putative keto/oxoacid ferredoxin oxidoreductase, alpha subunit.
  
 
 0.944
Dred_2825
2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: chy:CHY_0043 putative keto/oxoacid ferredoxin oxidoreductase, alpha subunit.
  
 
 0.938
Dred_0048
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: chy:CHY_0044 putative keto/oxoacid ferredoxin oxidoreductase, beta subunit.
  
 
 0.933
Dred_2824
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: chy:CHY_0044 putative keto/oxoacid ferredoxin oxidoreductase, beta subunit.
  
 
 0.933
Dred_1148
PFAM: aminotransferase, class I and II; KEGG: pca:Pcar_1888 aspartate aminotransferase.
  
 0.926
Dred_1696
L-aspartate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: mta:Moth_1490 aminotransferase, class I and II.
  
 0.926
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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