STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mthe_0300PFAM: ATP dependent DNA ligase; KEGG: mma:MM1307 hypothetical protein. (373 aa)    
Predicted Functional Partners:
Mthe_0938
Conserved hypothetical protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
 
     0.841
Mthe_0304
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: mma:MM1302 hypothetical protein.
 
     0.740
Mthe_0302
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: mac:MA4650 hypothetical protein.
 
     0.726
Mthe_0301
PFAM: CBS domain containing protein; KEGG: mbu:Mbur_1759 CBS domain protein.
       0.704
Mthe_0303
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: mma:MM1303 hypothetical protein.
       0.704
Mthe_0299
PFAM: LOR/SDH bifunctional enzyme conserved domain protein; KEGG: afu:AF1278 hypothetical protein.
       0.701
Mthe_0298
KEGG: mba:Mbar_A0300 hypothetical protein.
       0.693
Mthe_0830
KEGG: mka:MK1676 uncharacterized protein conserved in archaea; Belongs to the UPF0216 family.
  
     0.630
Mthe_0550
PFAM: Protein of unknown function DUF166; KEGG: mac:MA4432 hypothetical protein.
 
     0.584
mtd
Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
  
     0.521
Your Current Organism:
Methanothrix thermoacetophila
NCBI taxonomy Id: 349307
Other names: M. thermoacetophila PT, Methanosaeta thermophila PT, Methanothrix thermoacetophila PT, Methanothrix thermophila DSM 6194, Methanothrix thermophila PT
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