node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mthe_0325 | Mthe_0801 | Mthe_0325 | Mthe_0801 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: jan:Jann_0783 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | LL-diaminopimelate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: aae:aq_273 N-succinyldiaminopimelate aminotransferase. | 0.924 |
Mthe_0325 | Mthe_1253 | Mthe_0325 | Mthe_1253 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: jan:Jann_0783 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | KEGG: mbu:Mbur_1980 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.483 |
Mthe_0325 | argD | Mthe_0325 | Mthe_0313 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: jan:Jann_0783 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: mbu:Mbur_2204 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.966 |
Mthe_0325 | dapA | Mthe_0325 | Mthe_0826 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: jan:Jann_0783 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.532 |
Mthe_0325 | dapB | Mthe_0325 | Mthe_0825 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: jan:Jann_0783 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.707 |
Mthe_0325 | dapF | Mthe_0325 | Mthe_0454 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: jan:Jann_0783 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. | 0.963 |
Mthe_0325 | lysA | Mthe_0325 | Mthe_0745 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: jan:Jann_0783 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.532 |
Mthe_0801 | Mthe_0325 | Mthe_0801 | Mthe_0325 | LL-diaminopimelate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: aae:aq_273 N-succinyldiaminopimelate aminotransferase. | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: jan:Jann_0783 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | 0.924 |
Mthe_0801 | Mthe_1253 | Mthe_0801 | Mthe_1253 | LL-diaminopimelate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: aae:aq_273 N-succinyldiaminopimelate aminotransferase. | KEGG: mbu:Mbur_1980 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.423 |
Mthe_0801 | dapA | Mthe_0801 | Mthe_0826 | LL-diaminopimelate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: aae:aq_273 N-succinyldiaminopimelate aminotransferase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.447 |
Mthe_0801 | dapB | Mthe_0801 | Mthe_0825 | LL-diaminopimelate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: aae:aq_273 N-succinyldiaminopimelate aminotransferase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.924 |
Mthe_0801 | dapF | Mthe_0801 | Mthe_0454 | LL-diaminopimelate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: aae:aq_273 N-succinyldiaminopimelate aminotransferase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. | 0.950 |
Mthe_0801 | lysA | Mthe_0801 | Mthe_0745 | LL-diaminopimelate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: aae:aq_273 N-succinyldiaminopimelate aminotransferase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.785 |
Mthe_1136 | Mthe_1253 | Mthe_1136 | Mthe_1253 | TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; KEGG: mma:MM1618 aspartate-semialdehyde dehydrogenase. | KEGG: mbu:Mbur_1980 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.999 |
Mthe_1136 | argD | Mthe_1136 | Mthe_0313 | TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; KEGG: mma:MM1618 aspartate-semialdehyde dehydrogenase. | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: mbu:Mbur_2204 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.658 |
Mthe_1136 | carB | Mthe_1136 | Mthe_1254 | TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; KEGG: mma:MM1618 aspartate-semialdehyde dehydrogenase. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: mac:MA2143 carbamoyl-phosphate synthase (glutamine-hydrolyzing), large subunit. | 0.489 |
Mthe_1136 | dapA | Mthe_1136 | Mthe_0826 | TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; KEGG: mma:MM1618 aspartate-semialdehyde dehydrogenase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.978 |
Mthe_1136 | dapB | Mthe_1136 | Mthe_0825 | TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; KEGG: mma:MM1618 aspartate-semialdehyde dehydrogenase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.825 |
Mthe_1136 | dapF | Mthe_1136 | Mthe_0454 | TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; KEGG: mma:MM1618 aspartate-semialdehyde dehydrogenase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. | 0.866 |
Mthe_1136 | glyA | Mthe_1136 | Mthe_1241 | TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; KEGG: mma:MM1618 aspartate-semialdehyde dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.662 |