node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LCK_00551 | LCK_01475 | LCK_00551 | LCK_01475 | Homocysteine S-methyltransferase; COG2040E. | Methionine synthase II (cobalamin-independent); COG0620E. | 0.917 |
LCK_00551 | LCK_01477 | LCK_00551 | LCK_01477 | Homocysteine S-methyltransferase; COG2040E. | Methionine synthase II (cobalamin-independent); COG0620E. | 0.917 |
LCK_00551 | LCK_01478 | LCK_00551 | LCK_01478 | Homocysteine S-methyltransferase; COG2040E. | Cystathionine beta-lyase; COG0626E. | 0.919 |
LCK_00551 | hom | LCK_00551 | LCK_00723 | Homocysteine S-methyltransferase; COG2040E. | Homoserine dehydrogenase; COG0460E. | 0.823 |
LCK_00551 | luxS | LCK_00551 | LCK_01476 | Homocysteine S-methyltransferase; COG2040E. | LuxS protein involved in autoinducer AI2 synthesis; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.914 |
LCK_00551 | metB | LCK_00551 | LCK_01479 | Homocysteine S-methyltransferase; COG2040E. | Cystathionine gamma-synthase; COG0626E. | 0.919 |
LCK_00551 | thrB | LCK_00551 | LCK_00722 | Homocysteine S-methyltransferase; COG2040E. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.800 |
LCK_01131 | luxS | LCK_01131 | LCK_01476 | Nucleoside phosphorylase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | LuxS protein involved in autoinducer AI2 synthesis; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.984 |
LCK_01475 | LCK_00551 | LCK_01475 | LCK_00551 | Methionine synthase II (cobalamin-independent); COG0620E. | Homocysteine S-methyltransferase; COG2040E. | 0.917 |
LCK_01475 | LCK_01477 | LCK_01475 | LCK_01477 | Methionine synthase II (cobalamin-independent); COG0620E. | Methionine synthase II (cobalamin-independent); COG0620E. | 0.909 |
LCK_01475 | LCK_01478 | LCK_01475 | LCK_01478 | Methionine synthase II (cobalamin-independent); COG0620E. | Cystathionine beta-lyase; COG0626E. | 0.942 |
LCK_01475 | hom | LCK_01475 | LCK_00723 | Methionine synthase II (cobalamin-independent); COG0620E. | Homoserine dehydrogenase; COG0460E. | 0.857 |
LCK_01475 | luxS | LCK_01475 | LCK_01476 | Methionine synthase II (cobalamin-independent); COG0620E. | LuxS protein involved in autoinducer AI2 synthesis; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.918 |
LCK_01475 | metA | LCK_01475 | LCK_01480 | Methionine synthase II (cobalamin-independent); COG0620E. | Homoserine trans-succinylase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.469 |
LCK_01475 | metB | LCK_01475 | LCK_01479 | Methionine synthase II (cobalamin-independent); COG0620E. | Cystathionine gamma-synthase; COG0626E. | 0.942 |
LCK_01475 | thrB | LCK_01475 | LCK_00722 | Methionine synthase II (cobalamin-independent); COG0620E. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.821 |
LCK_01477 | LCK_00551 | LCK_01477 | LCK_00551 | Methionine synthase II (cobalamin-independent); COG0620E. | Homocysteine S-methyltransferase; COG2040E. | 0.917 |
LCK_01477 | LCK_01475 | LCK_01477 | LCK_01475 | Methionine synthase II (cobalamin-independent); COG0620E. | Methionine synthase II (cobalamin-independent); COG0620E. | 0.909 |
LCK_01477 | LCK_01478 | LCK_01477 | LCK_01478 | Methionine synthase II (cobalamin-independent); COG0620E. | Cystathionine beta-lyase; COG0626E. | 0.986 |
LCK_01477 | hom | LCK_01477 | LCK_00723 | Methionine synthase II (cobalamin-independent); COG0620E. | Homoserine dehydrogenase; COG0460E. | 0.857 |