node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HCH_00299 | dapF1 | HCH_00299 | HCH_00298 | Uncharacterized protein conserved in bacteria; COG3159. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.923 |
HCH_00299 | dapF2 | HCH_00299 | HCH_03641 | Uncharacterized protein conserved in bacteria; COG3159. | Diaminopimelate epimerase; TIGRFAMsMatches:TIGR00652. | 0.717 |
HCH_00299 | lysA | HCH_00299 | HCH_00297 | Uncharacterized protein conserved in bacteria; COG3159. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.626 |
HCH_00299 | xerC | HCH_00299 | HCH_00300 | Uncharacterized protein conserved in bacteria; COG3159. | Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.893 |
HCH_03695 | dapF1 | HCH_03695 | HCH_00298 | Diaminopimelate decarboxylase; COG0019. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.936 |
HCH_03695 | dapF2 | HCH_03695 | HCH_03641 | Diaminopimelate decarboxylase; COG0019. | Diaminopimelate epimerase; TIGRFAMsMatches:TIGR00652. | 0.936 |
HCH_03695 | lysA | HCH_03695 | HCH_00297 | Diaminopimelate decarboxylase; COG0019. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.929 |
HCH_03695 | murE | HCH_03695 | HCH_05888 | Diaminopimelate decarboxylase; COG0019. | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.919 |
asd | carB | HCH_02431 | HCH_01228 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Carbamoylphosphate synthase large subunit; COG0458; split gene in MJ; Belongs to the CarB family. | 0.471 |
asd | dapF1 | HCH_02431 | HCH_00298 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.747 |
asd | dapF2 | HCH_02431 | HCH_03641 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; TIGRFAMsMatches:TIGR00652. | 0.747 |
carB | asd | HCH_01228 | HCH_02431 | Carbamoylphosphate synthase large subunit; COG0458; split gene in MJ; Belongs to the CarB family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.471 |
carB | dapE | HCH_01228 | HCH_05260 | Carbamoylphosphate synthase large subunit; COG0458; split gene in MJ; Belongs to the CarB family. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.462 |
carB | dapF1 | HCH_01228 | HCH_00298 | Carbamoylphosphate synthase large subunit; COG0458; split gene in MJ; Belongs to the CarB family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.925 |
dapE | carB | HCH_05260 | HCH_01228 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Carbamoylphosphate synthase large subunit; COG0458; split gene in MJ; Belongs to the CarB family. | 0.462 |
dapE | dapF1 | HCH_05260 | HCH_00298 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.925 |
dapE | dapF2 | HCH_05260 | HCH_03641 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Diaminopimelate epimerase; TIGRFAMsMatches:TIGR00652. | 0.925 |
dapF1 | HCH_00299 | HCH_00298 | HCH_00299 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Uncharacterized protein conserved in bacteria; COG3159. | 0.923 |
dapF1 | HCH_03695 | HCH_00298 | HCH_03695 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Diaminopimelate decarboxylase; COG0019. | 0.936 |
dapF1 | asd | HCH_00298 | HCH_02431 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.747 |