STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceEPyruvate dehydrogenase complex, dehydrogenase (E1) component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (884 aa)    
Predicted Functional Partners:
aceF
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
lpdA1
Dihydrolipoamide dehydrogenase; TIGRFAMsMatches:TIGR01350.
 
 
 0.983
sucB1
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzyme COG0508.
 
 0.968
HCH_00152
Putative pyridine nucleotide-disulfide oxidoreductase, class I; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzyme COG1249.
  
 
 0.949
lpdA2
Dihydrolipoamide dehydrogenase; TIGRFAMsMatches:TIGR01350.
  
 
 0.949
pyk
Pyruvate kinase; TIGRFAMsMatches:TIGR01064; Belongs to the pyruvate kinase family.
  
 
 0.934
scfA
Malic enzyme; COG0281.
    
 0.931
oadA1
Oxaloacetate decarboxylase alpha subunit; TIGRFAMsMatches:TIGR01108.
  
 
 0.929
oadA2
Oxaloacetate decarboxylase alpha subunit; TIGRFAMsMatches:TIGR01108.
  
 
 0.929
sucB2
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
  
 
 0.917
Your Current Organism:
Hahella chejuensis
NCBI taxonomy Id: 349521
Other names: H. chejuensis KCTC 2396, Hahella chejuensis KCTC 2396, Hahella chejuensis str. KCTC 2396, Hahella chejuensis strain KCTC 2396
Server load: low (12%) [HD]