STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (341 aa)    
Predicted Functional Partners:
pyrC
Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
 
 
 0.991
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.990
HCH_00554
Dihydroorotase and related cyclic amidoHydrolase; COG0044.
 
 0.986
HCH_01704
Dihydroorotase and related cyclic amidoHydrolase; COG0044.
  
 0.984
HCH_00287
2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; COG0543.
  
 
 0.981
HCH_05046
Conserved hypothetical protein.
  
 
 0.980
carB
Carbamoylphosphate synthase large subunit; COG0458; split gene in MJ; Belongs to the CarB family.
 
 
 0.951
pyrB
Aspartate carbamoyltransferase; TIGRFAMsMatches:TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.933
carA
Carbamoylphosphate synthase small subunit; COG0505; Belongs to the CarA family.
 
  
 0.929
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.904
Your Current Organism:
Hahella chejuensis
NCBI taxonomy Id: 349521
Other names: H. chejuensis KCTC 2396, Hahella chejuensis KCTC 2396, Hahella chejuensis str. KCTC 2396, Hahella chejuensis strain KCTC 2396
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