node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HCH_01120 | HCH_03134 | HCH_01120 | HCH_03134 | SAM-dependent methyltransferase; COG0500. | 7-keto-8-aminopelargonate synthetase and related enzyme; COG0156. | 0.622 |
HCH_01120 | HCH_05369 | HCH_01120 | HCH_05369 | SAM-dependent methyltransferase; COG0500. | Predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily); COG0596. | 0.656 |
HCH_01120 | bioA | HCH_01120 | HCH_01529 | SAM-dependent methyltransferase; COG0500. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.476 |
HCH_01120 | bioB | HCH_01120 | HCH_05371 | SAM-dependent methyltransferase; COG0500. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.873 |
HCH_01120 | bioD | HCH_01120 | HCH_05366 | SAM-dependent methyltransferase; COG0500. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.835 |
HCH_01120 | bioF | HCH_01120 | HCH_05370 | SAM-dependent methyltransferase; COG0500. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.622 |
HCH_01120 | hapH | HCH_01120 | HCH_06031 | SAM-dependent methyltransferase; COG0500. | 7-keto-8-aminopelargonate synthetase and related enzyme; COG0156. | 0.622 |
HCH_03134 | HCH_01120 | HCH_03134 | HCH_01120 | 7-keto-8-aminopelargonate synthetase and related enzyme; COG0156. | SAM-dependent methyltransferase; COG0500. | 0.622 |
HCH_03134 | HCH_05369 | HCH_03134 | HCH_05369 | 7-keto-8-aminopelargonate synthetase and related enzyme; COG0156. | Predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily); COG0596. | 0.543 |
HCH_03134 | HCH_06234 | HCH_03134 | HCH_06234 | 7-keto-8-aminopelargonate synthetase and related enzyme; COG0156. | Biotin-(acetyl-CoA carboxylase) ligase; COG0340. | 0.481 |
HCH_03134 | bioA | HCH_03134 | HCH_01529 | 7-keto-8-aminopelargonate synthetase and related enzyme; COG0156. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.800 |
HCH_03134 | bioB | HCH_03134 | HCH_05371 | 7-keto-8-aminopelargonate synthetase and related enzyme; COG0156. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.779 |
HCH_03134 | bioC | HCH_03134 | HCH_05368 | 7-keto-8-aminopelargonate synthetase and related enzyme; COG0156. | SAM-dependent methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.695 |
HCH_03134 | bioD | HCH_03134 | HCH_05366 | 7-keto-8-aminopelargonate synthetase and related enzyme; COG0156. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.921 |
HCH_05369 | HCH_01120 | HCH_05369 | HCH_01120 | Predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily); COG0596. | SAM-dependent methyltransferase; COG0500. | 0.656 |
HCH_05369 | HCH_03134 | HCH_05369 | HCH_03134 | Predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily); COG0596. | 7-keto-8-aminopelargonate synthetase and related enzyme; COG0156. | 0.543 |
HCH_05369 | bioA | HCH_05369 | HCH_01529 | Predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily); COG0596. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.527 |
HCH_05369 | bioB | HCH_05369 | HCH_05371 | Predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily); COG0596. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.874 |
HCH_05369 | bioC | HCH_05369 | HCH_05368 | Predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily); COG0596. | SAM-dependent methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.969 |
HCH_05369 | bioD | HCH_05369 | HCH_05366 | Predicted Hydrolase or acyltransferase (alpha/beta hydrolase superfamily); COG0596. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.923 |