STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amuc_2070Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (751 aa)    
Predicted Functional Partners:
Amuc_1466
PFAM: FAD linked oxidase domain protein; KEGG: dol:Dole_0002 FAD linked oxidase domain protein.
   
 0.919
Amuc_1321
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: bfs:BF2360 putative thioredoxin peroxidase.
  
 
 0.752
msrB
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 
 0.673
Amuc_1592
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 0.649
Amuc_0214
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bja:bll7286 pyruvate dehydrogenase; Belongs to the TPP enzyme family.
  
 0.574
Amuc_0799
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mar:MAE_38140 pyruvate-flavodoxin oxidoreductase.
  
  
 0.551
Amuc_1880
PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: dra:DR_1540 isocitrate dehydrogenase.
  
 0.544
Amuc_2066
PFAM: Proline dehydrogenase; Aldehyde Dehydrogenase_; KEGG: pcu:pc0033 putative bifunctional protein (proline dehydrogenase and delta-1-pyrroline-5-carboxylate dehydrogenase); Belongs to the aldehyde dehydrogenase family.
  
 
 0.523
Amuc_1650
TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: olu:OSTLU_51596 predicted protein.
   
 0.515
Amuc_0946
TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: cbl:CLK_2154 DJ-1 family protein.
  
 
 0.506
Your Current Organism:
Akkermansia muciniphila
NCBI taxonomy Id: 349741
Other names: A. muciniphila ATCC BAA-835, Akkermansia muciniphila ATCC BAA-835, Akkermansia muciniphila Muc, Akkermansia muciniphila str. ATCC BAA-835, Akkermansia muciniphila strain ATCC BAA-835, Akkermansia sp. Muc
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