STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mflv_0307Malate dehydrogenase (NAD); TIGRFAM: L-lactate dehydrogenase; PFAM: Lactate/malate dehydrogenase; KEGG: mva:Mvan_0439 L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (344 aa)    
Predicted Functional Partners:
Mflv_2616
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mmc:Mmcs_3567 pyruvate flavodoxin/ferredoxin oxidoreductase-like protein.
  
 
 0.971
Mflv_0262
PFAM: pyruvate kinase; KEGG: mva:Mvan_0632 pyruvate kinase.
  
 0.968
Mflv_3591
PFAM: pyruvate kinase; KEGG: mmc:Mmcs_3042 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.968
Mflv_4198
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.949
Mflv_2617
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mmc:Mmcs_3566 thiamine pyrophosphate enzyme-like TPP-binding protein.
  
 
 0.945
Mflv_2214
PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: mmc:Mmcs_3977 malate dehydrogenase (oxaloacetate decarboxylating).
  
 0.942
Mflv_2781
2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.938
Mflv_3445
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: msm:MSMEG_5826 pyruvate decarboxylase; Belongs to the TPP enzyme family.
  
 0.928
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: mmc:Mmcs_4334 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.926
Mflv_1882
Pyruvate carboxylase; PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: mmc:Mmcs_4307 pyruvate carboxylase.
  
 0.919
Your Current Organism:
Mycolicibacterium gilvum
NCBI taxonomy Id: 350054
Other names: M. gilvum PYR-GCK, Mycobacterium flavescens ATCC 700033, Mycobacterium flavescens PYR-GCK, Mycobacterium gilvum PYR-GCK, Mycolicibacterium gilvum PYR-GCK
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