STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mflv_1521Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (306 aa)    
Predicted Functional Partners:
Mflv_1522
Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 0.999
Mflv_1520
PFAM: Hydratase/decarboxylase; KEGG: mmc:Mmcs_4661 4-oxalocrotonate decarboxylase.
 
  
 0.994
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.984
Mflv_0205
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.938
Mflv_1536
KEGG: mmc:Mmcs_4636 acetyl-CoA acyltransferase.
     
 0.912
Mflv_4952
PFAM: aldehyde dehydrogenase; KEGG: rha:RHA1_ro06081 dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.912
Mflv_0742
PFAM: aldehyde dehydrogenase; KEGG: mva:Mvan_0105 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.911
Mflv_0428
PFAM: aldehyde dehydrogenase; KEGG: mva:Mvan_0240 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.908
Mflv_1600
PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_4578 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.908
Mflv_1797
PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_4395 aldehyde dehydrogenase.
    
 0.908
Your Current Organism:
Mycolicibacterium gilvum
NCBI taxonomy Id: 350054
Other names: M. gilvum PYR-GCK, Mycobacterium flavescens ATCC 700033, Mycobacterium flavescens PYR-GCK, Mycobacterium gilvum PYR-GCK, Mycolicibacterium gilvum PYR-GCK
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