STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
otsATrehalose 6-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose and in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P). Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Probably also able to use ADP-Glc, CDP-Glc, GDP-Glc and TDP-Glc as glucosyl donors; Belongs to the glycosyltransferase 20 family. (503 aa)    
Predicted Functional Partners:
Mflv_1458
Trehalose 6-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
 0.998
Mflv_1897
UDP-glucose pyrophosphorylase; PFAM: Nucleotidyl transferase; KEGG: mmc:Mmcs_4290 nucleotidyl transferase.
    
 0.965
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
    
 0.958
Mflv_3449
PFAM: glycosyl transferase, group 1; KEGG: mmc:Mmcs_1278 glycosyl transferase, group 1.
    
 0.910
Mflv_4262
(1->4)-alpha-D-glucan synthase (ADP-glucose); PFAM: glycosyl transferase, group 1; KEGG: mpa:MAP3064 hypothetical protein.
    
 0.910
Mflv_1567
KEGG: mmc:Mmcs_4608 hypothetical protein.
       0.893
Mflv_3723
PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: mmc:Mmcs_4598 alpha amylase, catalytic region.
 
  
 0.849
Mflv_3632
KEGG: mva:Mvan_2785 malto-oligosyltrehalose synthase; TIGRFAM: malto-oligosyltrehalose synthase; PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain.
  
  
 0.835
Mflv_2676
PFAM: glycoside hydrolase 15-related; KEGG: mmc:Mmcs_3484 glycoside hydrolase 15-related.
 
   
 0.834
mak
Conserved hypothetical protein; Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity); Belongs to the aminoglycoside phosphotransferase family.
  
  
 0.817
Your Current Organism:
Mycolicibacterium gilvum
NCBI taxonomy Id: 350054
Other names: M. gilvum PYR-GCK, Mycobacterium flavescens ATCC 700033, Mycobacterium flavescens PYR-GCK, Mycobacterium gilvum PYR-GCK, Mycolicibacterium gilvum PYR-GCK
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