node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mflv_0942 | Mflv_1329 | Mflv_0942 | Mflv_1329 | PFAM: aldo/keto reductase; KEGG: nfa:nfa3270 putative oxidoreductase. | PFAM: aldo/keto reductase; KEGG: mva:Mvan_5463 aldo/keto reductase. | 0.914 |
Mflv_0942 | pdxH | Mflv_0942 | Mflv_1727 | PFAM: aldo/keto reductase; KEGG: nfa:nfa3270 putative oxidoreductase. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.905 |
Mflv_1329 | Mflv_0942 | Mflv_1329 | Mflv_0942 | PFAM: aldo/keto reductase; KEGG: mva:Mvan_5463 aldo/keto reductase. | PFAM: aldo/keto reductase; KEGG: nfa:nfa3270 putative oxidoreductase. | 0.914 |
Mflv_1329 | pdxH | Mflv_1329 | Mflv_1727 | PFAM: aldo/keto reductase; KEGG: mva:Mvan_5463 aldo/keto reductase. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.905 |
Mflv_1726 | Mflv_1729 | Mflv_1726 | Mflv_1729 | PFAM: Citrate synthase; KEGG: mva:Mvan_5025 citrate (Si)-synthase; Belongs to the citrate synthase family. | KEGG: mmc:Mmcs_4456 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | 0.956 |
Mflv_1726 | pdxH | Mflv_1726 | Mflv_1727 | PFAM: Citrate synthase; KEGG: mva:Mvan_5025 citrate (Si)-synthase; Belongs to the citrate synthase family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.762 |
Mflv_1729 | Mflv_1726 | Mflv_1729 | Mflv_1726 | KEGG: mmc:Mmcs_4456 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | PFAM: Citrate synthase; KEGG: mva:Mvan_5025 citrate (Si)-synthase; Belongs to the citrate synthase family. | 0.956 |
Mflv_1729 | pdxH | Mflv_1729 | Mflv_1727 | KEGG: mmc:Mmcs_4456 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.612 |
carB | pdxH | Mflv_3743 | Mflv_1727 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: mmc:Mmcs_2367 carbamoyl-phosphate synthase, large subunit. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.586 |
carB | pyrB | Mflv_3743 | Mflv_3747 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: mmc:Mmcs_2367 carbamoyl-phosphate synthase, large subunit. | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; KEGG: mmc:Mmcs_2363 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
fgd | pdxH | Mflv_0211 | Mflv_1727 | Luciferase family protein; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.795 |
fgd | ribH | Mflv_0211 | Mflv_3718 | Luciferase family protein; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.594 |
pdxH | Mflv_0942 | Mflv_1727 | Mflv_0942 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | PFAM: aldo/keto reductase; KEGG: nfa:nfa3270 putative oxidoreductase. | 0.905 |
pdxH | Mflv_1329 | Mflv_1727 | Mflv_1329 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | PFAM: aldo/keto reductase; KEGG: mva:Mvan_5463 aldo/keto reductase. | 0.905 |
pdxH | Mflv_1726 | Mflv_1727 | Mflv_1726 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | PFAM: Citrate synthase; KEGG: mva:Mvan_5025 citrate (Si)-synthase; Belongs to the citrate synthase family. | 0.762 |
pdxH | Mflv_1729 | Mflv_1727 | Mflv_1729 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | KEGG: mmc:Mmcs_4456 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | 0.612 |
pdxH | carB | Mflv_1727 | Mflv_3743 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: mmc:Mmcs_2367 carbamoyl-phosphate synthase, large subunit. | 0.586 |
pdxH | fgd | Mflv_1727 | Mflv_0211 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Luciferase family protein; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria. | 0.795 |
pdxH | pdxS | Mflv_1727 | Mflv_3832 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.955 |
pdxH | pdxT | Mflv_1727 | Mflv_3830 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.970 |