node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mflv_1524 | Mflv_4660 | Mflv_1524 | Mflv_4660 | KEGG: mmc:Mmcs_4657 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: mmc:Mmcs_1409 UvrD/REP helicase. | 0.485 |
Mflv_1524 | dinB-2 | Mflv_1524 | Mflv_3642 | KEGG: mmc:Mmcs_4657 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.564 |
Mflv_1524 | polA | Mflv_1524 | Mflv_3564 | KEGG: mmc:Mmcs_4657 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.923 |
Mflv_1524 | recA | Mflv_1524 | Mflv_3975 | KEGG: mmc:Mmcs_4657 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.941 |
Mflv_4660 | Mflv_1524 | Mflv_4660 | Mflv_1524 | ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: mmc:Mmcs_1409 UvrD/REP helicase. | KEGG: mmc:Mmcs_4657 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | 0.485 |
Mflv_4660 | dinB-2 | Mflv_4660 | Mflv_3642 | ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: mmc:Mmcs_1409 UvrD/REP helicase. | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.634 |
Mflv_4660 | polA | Mflv_4660 | Mflv_3564 | ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: mmc:Mmcs_1409 UvrD/REP helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.996 |
Mflv_4660 | radA | Mflv_4660 | Mflv_1442 | ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: mmc:Mmcs_1409 UvrD/REP helicase. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.617 |
Mflv_4660 | recA | Mflv_4660 | Mflv_3975 | ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: mmc:Mmcs_1409 UvrD/REP helicase. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.996 |
Mflv_4660 | recX | Mflv_4660 | Mflv_3974 | ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: mmc:Mmcs_1409 UvrD/REP helicase. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.508 |
Mflv_4660 | rpoA | Mflv_4660 | Mflv_4970 | ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: mmc:Mmcs_1409 UvrD/REP helicase. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.552 |
Mflv_4660 | rpoB | Mflv_4660 | Mflv_5097 | ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: mmc:Mmcs_1409 UvrD/REP helicase. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.851 |
Mflv_4660 | rpoC | Mflv_4660 | Mflv_5096 | ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: mmc:Mmcs_1409 UvrD/REP helicase. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.588 |
dinB-2 | Mflv_1524 | Mflv_3642 | Mflv_1524 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | KEGG: mmc:Mmcs_4657 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | 0.564 |
dinB-2 | Mflv_4660 | Mflv_3642 | Mflv_4660 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: mmc:Mmcs_1409 UvrD/REP helicase. | 0.634 |
dinB-2 | lexA | Mflv_3642 | Mflv_3956 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.882 |
dinB-2 | polA | Mflv_3642 | Mflv_3564 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.876 |
dinB-2 | recA | Mflv_3642 | Mflv_3975 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.937 |
lexA | dinB-2 | Mflv_3956 | Mflv_3642 | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.882 |
lexA | polA | Mflv_3956 | Mflv_3564 | SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.604 |