STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menGDemethylmenaquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (228 aa)    
Predicted Functional Partners:
menA
1,4-dihydroxy-2-naphtoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 0.927
Mflv_1845
Methyltransferase type 11; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: mmc:Mmcs_5079 methyltransferase type 12.
  
  
 
0.922
menD
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
     
 0.834
Mflv_5260
PFAM: glycosyl transferase, group 1; KEGG: mmc:Mmcs_0761 glycosyl transferase, group 1.
     
 0.757
menC
Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
     
 0.640
Mflv_5253
Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: mmc:Mmcs_0771 trans-hexaprenyltranstransferase; Belongs to the FPP/GGPP synthase family.
 
  
 0.620
Mflv_5259
PFAM: O-methyltransferase domain protein; KEGG: mva:Mvan_0979 O-methyltransferase domain protein.
       0.610
Mflv_4680
TIGRFAM: isochorismate synthases; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: mmc:Mmcs_1387 isochorismate synthases.
     
 0.580
tsaD
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
  
 0.569
Mflv_2721
TIGRFAM: putative deoxyguanosinetriphosphate triphosphohydrolase; SMART: metal-dependent phosphohydrolase, HD region; KEGG: mmc:Mmcs_3443 deoxyguanosinetriphosphate triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily.
     
 0.551
Your Current Organism:
Mycolicibacterium gilvum
NCBI taxonomy Id: 350054
Other names: M. gilvum PYR-GCK, Mycobacterium flavescens ATCC 700033, Mycobacterium flavescens PYR-GCK, Mycobacterium gilvum PYR-GCK, Mycolicibacterium gilvum PYR-GCK
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