node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mvan_0637 | Mvan_3258 | Mvan_0637 | Mvan_3258 | PFAM: regulatory protein, MerR; KEGG: mmc:Mmcs_0465 transcriptional regulator, MerR family. | KEGG: mmc:Mmcs_1428 hypothetical protein. | 0.534 |
Mvan_0637 | clpB | Mvan_0637 | Mvan_0659 | PFAM: regulatory protein, MerR; KEGG: mmc:Mmcs_0465 transcriptional regulator, MerR family. | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.733 |
Mvan_0637 | dnaJ | Mvan_0637 | Mvan_0636 | PFAM: regulatory protein, MerR; KEGG: mmc:Mmcs_0465 transcriptional regulator, MerR family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.991 |
Mvan_0637 | dnaJ-2 | Mvan_0637 | Mvan_3836 | PFAM: regulatory protein, MerR; KEGG: mmc:Mmcs_0465 transcriptional regulator, MerR family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.810 |
Mvan_0637 | dnaK | Mvan_0637 | Mvan_0634 | PFAM: regulatory protein, MerR; KEGG: mmc:Mmcs_0465 transcriptional regulator, MerR family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.990 |
Mvan_0637 | groL1 | Mvan_0637 | Mvan_0764 | PFAM: regulatory protein, MerR; KEGG: mmc:Mmcs_0465 transcriptional regulator, MerR family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.489 |
Mvan_0637 | groL2 | Mvan_0637 | Mvan_1495 | PFAM: regulatory protein, MerR; KEGG: mmc:Mmcs_0465 transcriptional regulator, MerR family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.608 |
Mvan_0637 | groS | Mvan_0637 | Mvan_1494 | PFAM: regulatory protein, MerR; KEGG: mmc:Mmcs_0465 transcriptional regulator, MerR family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.559 |
Mvan_0637 | grpE | Mvan_0637 | Mvan_0635 | PFAM: regulatory protein, MerR; KEGG: mmc:Mmcs_0465 transcriptional regulator, MerR family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.982 |
Mvan_3258 | Mvan_0637 | Mvan_3258 | Mvan_0637 | KEGG: mmc:Mmcs_1428 hypothetical protein. | PFAM: regulatory protein, MerR; KEGG: mmc:Mmcs_0465 transcriptional regulator, MerR family. | 0.534 |
Mvan_3258 | clpB | Mvan_3258 | Mvan_0659 | KEGG: mmc:Mmcs_1428 hypothetical protein. | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.675 |
Mvan_3258 | dnaK | Mvan_3258 | Mvan_0634 | KEGG: mmc:Mmcs_1428 hypothetical protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.850 |
Mvan_3258 | groL1 | Mvan_3258 | Mvan_0764 | KEGG: mmc:Mmcs_1428 hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.787 |
Mvan_3258 | groL2 | Mvan_3258 | Mvan_1495 | KEGG: mmc:Mmcs_1428 hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.787 |
Mvan_3258 | groS | Mvan_3258 | Mvan_1494 | KEGG: mmc:Mmcs_1428 hypothetical protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.615 |
Mvan_3258 | grpE | Mvan_3258 | Mvan_0635 | KEGG: mmc:Mmcs_1428 hypothetical protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.842 |
Mvan_3258 | htpG | Mvan_3258 | Mvan_1817 | KEGG: mmc:Mmcs_1428 hypothetical protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.922 |
clpB | Mvan_0637 | Mvan_0659 | Mvan_0637 | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | PFAM: regulatory protein, MerR; KEGG: mmc:Mmcs_0465 transcriptional regulator, MerR family. | 0.733 |
clpB | Mvan_3258 | Mvan_0659 | Mvan_3258 | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | KEGG: mmc:Mmcs_1428 hypothetical protein. | 0.675 |
clpB | dnaJ | Mvan_0659 | Mvan_0636 | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.944 |