STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: mmc:Mmcs_0690 glutamate-1-semialdehyde-2,1-aminomutase. (432 aa)    
Predicted Functional Partners:
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.997
Mvan_0847
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mmc:Mmcs_0679 porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.997
Mvan_0865
PFAM: Phosphoglycerate mutase; KEGG: mmc:Mmcs_0691 phosphoglycerate mutase.
  
    0.966
Mvan_0866
PFAM: Redoxin domain protein; KEGG: mmc:Mmcs_0692 redoxin.
  
  
 0.953
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.946
Mvan_0867
PFAM: cytochrome c biogenesis protein, transmembrane region; KEGG: mmc:Mmcs_0693 cytochrome c biogenesis protein, transmembrane region.
  
  
 0.929
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.921
Mvan_0869
PFAM: cytochrome c assembly protein; KEGG: mmc:Mmcs_0695 cytochrome c assembly protein.
 
  
 0.912
Mvan_0868
PFAM: ResB family protein; KEGG: mmc:Mmcs_0694 ResB-like protein.
  
  
 0.902
Mvan_3847
PFAM: beta-ketoacyl synthase; KEGG: mmc:Mmcs_3468 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
    
 0.836
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.