node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mvan_2222 | frr | Mvan_2222 | Mvan_2221 | PFAM: phosphatidate cytidylyltransferase; KEGG: mmc:Mmcs_2005 phosphatidate cytidylyltransferase; Belongs to the CDS family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.908 |
Mvan_2222 | pyrH | Mvan_2222 | Mvan_2220 | PFAM: phosphatidate cytidylyltransferase; KEGG: mmc:Mmcs_2005 phosphatidate cytidylyltransferase; Belongs to the CDS family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.909 |
Mvan_2222 | rlmN | Mvan_2222 | Mvan_2223 | PFAM: phosphatidate cytidylyltransferase; KEGG: mmc:Mmcs_2005 phosphatidate cytidylyltransferase; Belongs to the CDS family. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.777 |
Mvan_2688 | miaB | Mvan_2688 | Mvan_2429 | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: mmc:Mmcs_2384 Fmu (Sun); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.712 |
Mvan_2688 | pyrH | Mvan_2688 | Mvan_2220 | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: mmc:Mmcs_2384 Fmu (Sun); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.411 |
Mvan_2688 | rlmN | Mvan_2688 | Mvan_2223 | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: mmc:Mmcs_2384 Fmu (Sun); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.940 |
Mvan_2688 | rsmH | Mvan_2688 | Mvan_3531 | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: mmc:Mmcs_2384 Fmu (Sun); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.578 |
Mvan_2688 | trmD | Mvan_2688 | Mvan_2190 | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: mmc:Mmcs_2384 Fmu (Sun); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.496 |
Mvan_3855 | Mvan_5346 | Mvan_3855 | Mvan_5346 | Coproporphyrinogen III oxidase, anaerobic; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: mpa:MAP0469c A/G-specific adenine glycosylase. | 0.536 |
Mvan_3855 | miaB | Mvan_3855 | Mvan_2429 | Coproporphyrinogen III oxidase, anaerobic; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.623 |
Mvan_3855 | rlmN | Mvan_3855 | Mvan_2223 | Coproporphyrinogen III oxidase, anaerobic; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.600 |
Mvan_5346 | Mvan_3855 | Mvan_5346 | Mvan_3855 | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: mpa:MAP0469c A/G-specific adenine glycosylase. | Coproporphyrinogen III oxidase, anaerobic; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.536 |
Mvan_5346 | rlmN | Mvan_5346 | Mvan_2223 | HhH-GPD family protein; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: mpa:MAP0469c A/G-specific adenine glycosylase. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.691 |
Mvan_5430 | rlmN | Mvan_5430 | Mvan_2223 | PFAM: peptidase S1 and S6, chymotrypsin/Hap; Colicin V production protein; KEGG: mmc:Mmcs_4813 colicin V production protein. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.665 |
frr | Mvan_2222 | Mvan_2221 | Mvan_2222 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | PFAM: phosphatidate cytidylyltransferase; KEGG: mmc:Mmcs_2005 phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.908 |
frr | pyrH | Mvan_2221 | Mvan_2220 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.977 |
frr | rlmN | Mvan_2221 | Mvan_2223 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.828 |
frr | rsmH | Mvan_2221 | Mvan_3531 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.675 |
frr | trmD | Mvan_2221 | Mvan_2190 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.481 |
miaB | Mvan_2688 | Mvan_2429 | Mvan_2688 | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: mmc:Mmcs_2384 Fmu (Sun); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.712 |