node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mvan_0557 | panB | Mvan_0557 | Mvan_3602 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.932 |
Mvan_0557 | panC | Mvan_0557 | Mvan_5364 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.934 |
Mvan_3573 | Mvan_4516 | Mvan_3573 | Mvan_4516 | KEGG: mmc:Mmcs_3308 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. | PFAM: aminotransferase, class IV; KEGG: afm:Afu7g06900 branched-chain amino acid aminotransferase protein. | 0.904 |
Mvan_3573 | ilvD | Mvan_3573 | Mvan_0173 | KEGG: mmc:Mmcs_3308 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. | KEGG: mmc:Mmcs_0146 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.984 |
Mvan_3573 | ilvD-2 | Mvan_3573 | Mvan_1161 | KEGG: mmc:Mmcs_3308 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. | KEGG: sco:SCO3345 dihydroxy acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.982 |
Mvan_3573 | panB | Mvan_3573 | Mvan_3602 | KEGG: mmc:Mmcs_3308 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.917 |
Mvan_4516 | Mvan_3573 | Mvan_4516 | Mvan_3573 | PFAM: aminotransferase, class IV; KEGG: afm:Afu7g06900 branched-chain amino acid aminotransferase protein. | KEGG: mmc:Mmcs_3308 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. | 0.904 |
Mvan_4516 | ilvD | Mvan_4516 | Mvan_0173 | PFAM: aminotransferase, class IV; KEGG: afm:Afu7g06900 branched-chain amino acid aminotransferase protein. | KEGG: mmc:Mmcs_0146 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.967 |
Mvan_4516 | ilvD-2 | Mvan_4516 | Mvan_1161 | PFAM: aminotransferase, class IV; KEGG: afm:Afu7g06900 branched-chain amino acid aminotransferase protein. | KEGG: sco:SCO3345 dihydroxy acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.967 |
Mvan_4516 | panB | Mvan_4516 | Mvan_3602 | PFAM: aminotransferase, class IV; KEGG: afm:Afu7g06900 branched-chain amino acid aminotransferase protein. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.913 |
ilvD | Mvan_3573 | Mvan_0173 | Mvan_3573 | KEGG: mmc:Mmcs_0146 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | KEGG: mmc:Mmcs_3308 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. | 0.984 |
ilvD | Mvan_4516 | Mvan_0173 | Mvan_4516 | KEGG: mmc:Mmcs_0146 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | PFAM: aminotransferase, class IV; KEGG: afm:Afu7g06900 branched-chain amino acid aminotransferase protein. | 0.967 |
ilvD | ilvD-2 | Mvan_0173 | Mvan_1161 | KEGG: mmc:Mmcs_0146 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | KEGG: sco:SCO3345 dihydroxy acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.909 |
ilvD | panB | Mvan_0173 | Mvan_3602 | KEGG: mmc:Mmcs_0146 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.927 |
ilvD-2 | Mvan_3573 | Mvan_1161 | Mvan_3573 | KEGG: sco:SCO3345 dihydroxy acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | KEGG: mmc:Mmcs_3308 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV. | 0.982 |
ilvD-2 | Mvan_4516 | Mvan_1161 | Mvan_4516 | KEGG: sco:SCO3345 dihydroxy acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | PFAM: aminotransferase, class IV; KEGG: afm:Afu7g06900 branched-chain amino acid aminotransferase protein. | 0.967 |
ilvD-2 | ilvD | Mvan_1161 | Mvan_0173 | KEGG: sco:SCO3345 dihydroxy acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | KEGG: mmc:Mmcs_0146 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.909 |
ilvD-2 | panB | Mvan_1161 | Mvan_3602 | KEGG: sco:SCO3345 dihydroxy acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.927 |
mpa | pafA | Mvan_3458 | Mvan_3445 | Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Protein of unknown function DUF245 domain protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.969 |
mpa | panB | Mvan_3458 | Mvan_3602 | Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.673 |