STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
kdpAPotassium-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (556 aa)    
Predicted Functional Partners:
kdpB
K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
 
 0.999
kdpC
K+ transporting ATPase, KdpC subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
 0.999
Mvan_4762
Osmosensitive K+ channel signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Osmosensitive K+ channel His kinase sensor; UspA domain protein; KEGG: mmc:Mmcs_4229 osmosensitive K+ channel signal transduction histidine kinase.
 
  
 0.986
Mvan_4763
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mmc:Mmcs_4230 two component transcriptional regulator, winged helix family.
 
  
 0.928
Mvan_4758
Hypothetical protein.
     
 0.897
Mvan_0703
PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: mmc:Mmcs_0540 serine/threonine protein kinase.
   
  
 0.617
mprB
Integral membrane sensor signal transduction histidine kinase; Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. In response to environmental signals MprB acts as both a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to MprA, and a protein phosphatase that dephosphorylates phospho-MprA (By similarity).
  
  
 0.603
Mvan_5263
PFAM: GAF domain protein; KEGG: mmc:Mmcs_3585 putative GAF sensor protein.
  
  
 0.602
Mvan_4757
Hypothetical protein; KEGG: mpa:MAP0986c putative diaminopimelate decarboxylase.
       0.552
Mvan_0991
TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; Lycopene beta and epsilon cyclase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mmc:Mmcs_0770 geranylgeranyl reductase.
      
 0.527
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.