node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mvan_0162 | rskA | Mvan_0162 | Mvan_4928 | RNA polymerase, sigma subunit, SigZ; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: rba:RB6078 RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. | Conserved hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degradi [...] | 0.838 |
Mvan_0162 | sigK | Mvan_0162 | Mvan_4927 | RNA polymerase, sigma subunit, SigZ; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: rba:RB6078 RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. | RNA polymerase, sigma-24 subunit, ECF subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (By similarity). | 0.411 |
Mvan_0874 | Mvan_0876 | Mvan_0874 | Mvan_0876 | KEGG: mmc:Mmcs_5160 hypothetical protein. | KEGG: mmc:Mmcs_5162 hypothetical protein. | 0.949 |
Mvan_0874 | rskA | Mvan_0874 | Mvan_4928 | KEGG: mmc:Mmcs_5160 hypothetical protein. | Conserved hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degradi [...] | 0.533 |
Mvan_0876 | Mvan_0874 | Mvan_0876 | Mvan_0874 | KEGG: mmc:Mmcs_5162 hypothetical protein. | KEGG: mmc:Mmcs_5160 hypothetical protein. | 0.949 |
Mvan_0876 | Mvan_3530 | Mvan_0876 | Mvan_3530 | KEGG: mmc:Mmcs_5162 hypothetical protein. | KEGG: mmc:Mmcs_3263 FHA domain containing protein. | 0.509 |
Mvan_0876 | rskA | Mvan_0876 | Mvan_4928 | KEGG: mmc:Mmcs_5162 hypothetical protein. | Conserved hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degradi [...] | 0.598 |
Mvan_3530 | Mvan_0876 | Mvan_3530 | Mvan_0876 | KEGG: mmc:Mmcs_3263 FHA domain containing protein. | KEGG: mmc:Mmcs_5162 hypothetical protein. | 0.509 |
Mvan_3530 | Mvan_4461 | Mvan_3530 | Mvan_4461 | KEGG: mmc:Mmcs_3263 FHA domain containing protein. | TIGRFAM: H+ Antiporter protein; PFAM: major facilitator superfamily MFS_1; KEGG: mmc:Mmcs_3958 drug antiporter protein. | 0.543 |
Mvan_3530 | rskA | Mvan_3530 | Mvan_4928 | KEGG: mmc:Mmcs_3263 FHA domain containing protein. | Conserved hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degradi [...] | 0.464 |
Mvan_4461 | Mvan_3530 | Mvan_4461 | Mvan_3530 | TIGRFAM: H+ Antiporter protein; PFAM: major facilitator superfamily MFS_1; KEGG: mmc:Mmcs_3958 drug antiporter protein. | KEGG: mmc:Mmcs_3263 FHA domain containing protein. | 0.543 |
Mvan_4461 | rskA | Mvan_4461 | Mvan_4928 | TIGRFAM: H+ Antiporter protein; PFAM: major facilitator superfamily MFS_1; KEGG: mmc:Mmcs_3958 drug antiporter protein. | Conserved hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degradi [...] | 0.456 |
Mvan_4924 | Mvan_4925 | Mvan_4924 | Mvan_4925 | Hypothetical protein. | PFAM: protein of unknown function DUF867; KEGG: mmc:Mmcs_4367 protein of unknown function DUF867. | 0.671 |
Mvan_4924 | Mvan_4926 | Mvan_4924 | Mvan_4926 | Hypothetical protein. | PFAM: protein of unknown function DUF1365; KEGG: mmc:Mmcs_4370 protein of unknown function DUF1365. | 0.442 |
Mvan_4924 | rskA | Mvan_4924 | Mvan_4928 | Hypothetical protein. | Conserved hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degradi [...] | 0.442 |
Mvan_4924 | sigK | Mvan_4924 | Mvan_4927 | Hypothetical protein. | RNA polymerase, sigma-24 subunit, ECF subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (By similarity). | 0.442 |
Mvan_4925 | Mvan_4924 | Mvan_4925 | Mvan_4924 | PFAM: protein of unknown function DUF867; KEGG: mmc:Mmcs_4367 protein of unknown function DUF867. | Hypothetical protein. | 0.671 |
Mvan_4925 | Mvan_4926 | Mvan_4925 | Mvan_4926 | PFAM: protein of unknown function DUF867; KEGG: mmc:Mmcs_4367 protein of unknown function DUF867. | PFAM: protein of unknown function DUF1365; KEGG: mmc:Mmcs_4370 protein of unknown function DUF1365. | 0.500 |
Mvan_4925 | rskA | Mvan_4925 | Mvan_4928 | PFAM: protein of unknown function DUF867; KEGG: mmc:Mmcs_4367 protein of unknown function DUF867. | Conserved hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degradi [...] | 0.500 |
Mvan_4925 | sigK | Mvan_4925 | Mvan_4927 | PFAM: protein of unknown function DUF867; KEGG: mmc:Mmcs_4367 protein of unknown function DUF867. | RNA polymerase, sigma-24 subunit, ECF subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (By similarity). | 0.500 |