STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyp51Cytochrome P450; Its precise biological substrate is not known. Catalyzes C14- demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. Belongs to the cytochrome P450 family. (452 aa)    
Predicted Functional Partners:
Mvan_5163
KEGG: mmc:Mmcs_4584 hypothetical protein.
 
    0.987
Mvan_5160
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: mmc:Mmcs_4581 short-chain dehydrogenase/reductase SDR.
 
    0.979
fdx-2
KEGG: mmc:Mmcs_4583 hypothetical protein.
 
  
 0.967
Mvan_5159
PFAM: cytochrome P450; KEGG: mpa:MAP0600c putative cytochrome P450.
 
  
0.954
Mvan_5158
PFAM: regulatory protein, TetR; KEGG: mmc:Mmcs_4579 transcriptional regulator, TetR family.
 
     0.939
Mvan_5157
PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_4578 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
 0.897
Mvan_5155
PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: mmc:Mmcs_4576 6-phosphogluconate dehydrogenase, NAD-binding protein.
 
    0.895
Mvan_3124
PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR; KEGG: mbo:Mb2959 phenolpthiocerol synthesis type-I polyketide synthase PpsD.
  
 0.878
Mvan_3126
PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR; KEGG: mmc:Mmcs_2835 beta-ketoacyl synthase.
  
 0.878
Mvan_5153
KEGG: mmc:Mmcs_4574 hypothetical protein.
 
   
 0.870
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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