STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (311 aa)    
Predicted Functional Partners:
panD
L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 
 0.999
panB
Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.996
coaX
Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
  
 
 0.996
Mvan_5365
KEGG: mmc:Mmcs_4763 NAD-dependent glycerol-3-phosphate dehydrogenase-like protein.
   
 0.989
Mvan_1483
KEGG: mmc:Mmcs_1145 glutamate decarboxylase; TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; Belongs to the group II decarboxylase family.
  
 
 0.943
Mvan_0557
Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.934
coaA
KEGG: mmc:Mmcs_4133 pantothenate kinase; TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase.
    
 0.930
cmk
KEGG: mmc:Mmcs_2928 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
      0.908
Mvan_0105
PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_0090 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.904
Mvan_0240
PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_0217 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.904
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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