STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mvan_6057PFAM: protein of unknown function DUF179; KEGG: mmc:Mmcs_5392 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family. (201 aa)    
Predicted Functional Partners:
Mvan_1398
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
   
 0.961
Mvan_2042
Ribonucleoside-diphosphate reductase class Ib alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
   
 0.961
Mvan_2641
Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
  
  
 0.756
Mvan_4778
PFAM: regulatory protein, TetR; KEGG: mmc:Mmcs_4247 transcriptional regulator, TetR family.
   
    0.756
Mvan_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 
 0.725
Mvan_1294
PFAM: regulatory protein, TetR; KEGG: mmc:Mmcs_0998 transcriptional regulator, TetR family.
   
    0.723
Mvan_3780
Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR; KEGG: mpa:MAP0008c hypothetical protein.
   
    0.721
Mvan_2347
PFAM: iron dependent repressor; FeoA family protein; KEGG: mmc:Mmcs_2097 iron (metal) dependent repressor, DtxR family.
   
    0.716
Mvan_4569
PFAM: regulatory protein GntR, HTH; KEGG: mmc:Mmcs_4061 transcriptional regulator, GntR family.
  
    0.706
Mvan_6058
PFAM: major facilitator superfamily MFS_1; KEGG: mmc:Mmcs_5393 putative conserved integral membrane protein.
       0.702
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
Server load: medium (66%) [HD]