node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clos_0534 | Clos_1328 | Clos_0534 | Clos_1328 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | 0.463 |
Clos_0534 | Clos_1329 | Clos_0534 | Clos_1329 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: cth:Cthe_2529 porphobilinogen synthase; Belongs to the ALAD family. | 0.408 |
Clos_0534 | coaE | Clos_0534 | Clos_1207 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.528 |
Clos_0534 | gltX | Clos_0534 | Clos_0467 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.773 |
Clos_0534 | hemL | Clos_0534 | Clos_1330 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: cth:Cthe_2530 glutamate-1-semialdehyde-2,1-aminomutase. | 0.728 |
Clos_0534 | thiE | Clos_0534 | Clos_2693 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.517 |
Clos_1325 | Clos_1326 | Clos_1325 | Clos_1326 | Hypothetical protein. | TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | 0.972 |
Clos_1325 | Clos_1328 | Clos_1325 | Clos_1328 | Hypothetical protein. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | 0.946 |
Clos_1325 | Clos_1329 | Clos_1325 | Clos_1329 | Hypothetical protein. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: cth:Cthe_2529 porphobilinogen synthase; Belongs to the ALAD family. | 0.838 |
Clos_1325 | hemA | Clos_1325 | Clos_1324 | Hypothetical protein. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.800 |
Clos_1325 | hemC | Clos_1325 | Clos_1327 | Hypothetical protein. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.850 |
Clos_1325 | hemL | Clos_1325 | Clos_1330 | Hypothetical protein. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: cth:Cthe_2530 glutamate-1-semialdehyde-2,1-aminomutase. | 0.833 |
Clos_1326 | Clos_1325 | Clos_1326 | Clos_1325 | TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | Hypothetical protein. | 0.972 |
Clos_1326 | Clos_1328 | Clos_1326 | Clos_1328 | TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | 0.999 |
Clos_1326 | Clos_1329 | Clos_1326 | Clos_1329 | TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: cth:Cthe_2529 porphobilinogen synthase; Belongs to the ALAD family. | 0.965 |
Clos_1326 | gltX | Clos_1326 | Clos_0467 | TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.403 |
Clos_1326 | hemA | Clos_1326 | Clos_1324 | TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.970 |
Clos_1326 | hemC | Clos_1326 | Clos_1327 | TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.982 |
Clos_1326 | hemL | Clos_1326 | Clos_1330 | TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: cth:Cthe_2530 glutamate-1-semialdehyde-2,1-aminomutase. | 0.944 |
Clos_1328 | Clos_0534 | Clos_1328 | Clos_0534 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | 0.463 |