node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clos_1373 | Clos_1378 | Clos_1373 | Clos_1378 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cdf:CD2656 stage V sporulation protein D (sporulation specific penicillin-binding protein). | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cdf:CD2652 cell division/stage V sporulation protein; Belongs to the SEDS family. | 0.973 |
Clos_1373 | Clos_2017 | Clos_1373 | Clos_2017 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cdf:CD2656 stage V sporulation protein D (sporulation specific penicillin-binding protein). | TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: aae:aq_1747 UDP-MurNac-tripeptide synthetase; Belongs to the MurCDEF family. MurE subfamily. | 0.716 |
Clos_1373 | mraY | Clos_1373 | Clos_1376 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cdf:CD2656 stage V sporulation protein D (sporulation specific penicillin-binding protein). | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.947 |
Clos_1373 | murA | Clos_1373 | Clos_1380 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cdf:CD2656 stage V sporulation protein D (sporulation specific penicillin-binding protein). | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.703 |
Clos_1373 | murC | Clos_1373 | Clos_2649 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cdf:CD2656 stage V sporulation protein D (sporulation specific penicillin-binding protein). | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.898 |
Clos_1373 | murD | Clos_1373 | Clos_1377 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cdf:CD2656 stage V sporulation protein D (sporulation specific penicillin-binding protein). | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.938 |
Clos_1373 | murE | Clos_1373 | Clos_1374 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cdf:CD2656 stage V sporulation protein D (sporulation specific penicillin-binding protein). | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.869 |
Clos_1373 | murF | Clos_1373 | Clos_1375 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cdf:CD2656 stage V sporulation protein D (sporulation specific penicillin-binding protein). | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.955 |
Clos_1373 | murG | Clos_1373 | Clos_1379 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cdf:CD2656 stage V sporulation protein D (sporulation specific penicillin-binding protein). | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.850 |
Clos_1373 | uppP | Clos_1373 | Clos_0946 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cdf:CD2656 stage V sporulation protein D (sporulation specific penicillin-binding protein). | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.417 |
Clos_1378 | Clos_1373 | Clos_1378 | Clos_1373 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cdf:CD2652 cell division/stage V sporulation protein; Belongs to the SEDS family. | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cdf:CD2656 stage V sporulation protein D (sporulation specific penicillin-binding protein). | 0.973 |
Clos_1378 | Clos_2017 | Clos_1378 | Clos_2017 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cdf:CD2652 cell division/stage V sporulation protein; Belongs to the SEDS family. | TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: aae:aq_1747 UDP-MurNac-tripeptide synthetase; Belongs to the MurCDEF family. MurE subfamily. | 0.566 |
Clos_1378 | mraY | Clos_1378 | Clos_1376 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cdf:CD2652 cell division/stage V sporulation protein; Belongs to the SEDS family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.951 |
Clos_1378 | murA | Clos_1378 | Clos_1380 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cdf:CD2652 cell division/stage V sporulation protein; Belongs to the SEDS family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.822 |
Clos_1378 | murC | Clos_1378 | Clos_2649 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cdf:CD2652 cell division/stage V sporulation protein; Belongs to the SEDS family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.852 |
Clos_1378 | murD | Clos_1378 | Clos_1377 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cdf:CD2652 cell division/stage V sporulation protein; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.961 |
Clos_1378 | murE | Clos_1378 | Clos_1374 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cdf:CD2652 cell division/stage V sporulation protein; Belongs to the SEDS family. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.796 |
Clos_1378 | murF | Clos_1378 | Clos_1375 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cdf:CD2652 cell division/stage V sporulation protein; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.949 |
Clos_1378 | murG | Clos_1378 | Clos_1379 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cdf:CD2652 cell division/stage V sporulation protein; Belongs to the SEDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.982 |
Clos_2017 | Clos_1373 | Clos_2017 | Clos_1373 | TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: aae:aq_1747 UDP-MurNac-tripeptide synthetase; Belongs to the MurCDEF family. MurE subfamily. | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cdf:CD2656 stage V sporulation protein D (sporulation specific penicillin-binding protein). | 0.716 |