node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clos_0298 | Clos_2017 | Clos_0298 | Clos_2017 | TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: amt:Amet_1618 UDP-N-acetylmuramyl-tripeptide synthetase; Belongs to the MurCDEF family. MurE subfamily. | TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: aae:aq_1747 UDP-MurNac-tripeptide synthetase; Belongs to the MurCDEF family. MurE subfamily. | 0.917 |
Clos_0298 | dapF | Clos_0298 | Clos_1420 | TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: amt:Amet_1618 UDP-N-acetylmuramyl-tripeptide synthetase; Belongs to the MurCDEF family. MurE subfamily. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.926 |
Clos_0298 | murE | Clos_0298 | Clos_1374 | TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: amt:Amet_1618 UDP-N-acetylmuramyl-tripeptide synthetase; Belongs to the MurCDEF family. MurE subfamily. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.921 |
Clos_0545 | Clos_2023 | Clos_0545 | Clos_2023 | KEGG: tte:TTE1382 Aspartokinases; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the aspartokinase family. | PFAM: aminotransferase class I and II; KEGG: csc:Csac_0772 aminotransferase, class I and II. | 0.427 |
Clos_0545 | asd | Clos_0545 | Clos_1162 | KEGG: tte:TTE1382 Aspartokinases; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.996 |
Clos_0545 | dapA | Clos_0545 | Clos_1163 | KEGG: tte:TTE1382 Aspartokinases; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.855 |
Clos_0545 | dapB | Clos_0545 | Clos_1164 | KEGG: tte:TTE1382 Aspartokinases; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the aspartokinase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.830 |
Clos_0545 | dapF | Clos_0545 | Clos_1420 | KEGG: tte:TTE1382 Aspartokinases; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the aspartokinase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.788 |
Clos_1421 | Clos_1431 | Clos_1421 | Clos_1431 | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: cth:Cthe_1317 hypothetical protein. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.680 |
Clos_1421 | dapF | Clos_1421 | Clos_1420 | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: cth:Cthe_1317 hypothetical protein. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.713 |
Clos_1431 | Clos_1421 | Clos_1431 | Clos_1421 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: cth:Cthe_1317 hypothetical protein. | 0.680 |
Clos_1431 | dapF | Clos_1431 | Clos_1420 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.769 |
Clos_2017 | Clos_0298 | Clos_2017 | Clos_0298 | TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: aae:aq_1747 UDP-MurNac-tripeptide synthetase; Belongs to the MurCDEF family. MurE subfamily. | TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: amt:Amet_1618 UDP-N-acetylmuramyl-tripeptide synthetase; Belongs to the MurCDEF family. MurE subfamily. | 0.917 |
Clos_2017 | dapF | Clos_2017 | Clos_1420 | TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: aae:aq_1747 UDP-MurNac-tripeptide synthetase; Belongs to the MurCDEF family. MurE subfamily. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.928 |
Clos_2017 | murE | Clos_2017 | Clos_1374 | TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: aae:aq_1747 UDP-MurNac-tripeptide synthetase; Belongs to the MurCDEF family. MurE subfamily. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.924 |
Clos_2023 | Clos_0545 | Clos_2023 | Clos_0545 | PFAM: aminotransferase class I and II; KEGG: csc:Csac_0772 aminotransferase, class I and II. | KEGG: tte:TTE1382 Aspartokinases; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; Belongs to the aspartokinase family. | 0.427 |
Clos_2023 | asd | Clos_2023 | Clos_1162 | PFAM: aminotransferase class I and II; KEGG: csc:Csac_0772 aminotransferase, class I and II. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.444 |
Clos_2023 | dapA | Clos_2023 | Clos_1163 | PFAM: aminotransferase class I and II; KEGG: csc:Csac_0772 aminotransferase, class I and II. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.484 |
Clos_2023 | dapB | Clos_2023 | Clos_1164 | PFAM: aminotransferase class I and II; KEGG: csc:Csac_0772 aminotransferase, class I and II. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.927 |
Clos_2023 | dapF | Clos_2023 | Clos_1420 | PFAM: aminotransferase class I and II; KEGG: csc:Csac_0772 aminotransferase, class I and II. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.956 |