node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clos_0534 | Clos_0920 | Clos_0534 | Clos_0920 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | 5'-Nucleotidase domain protein; PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bcl:ABC0966 nucleotidase; Belongs to the 5'-nucleotidase family. | 0.965 |
Clos_0534 | Clos_1353 | Clos_0534 | Clos_1353 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | KEGG: tte:TTE2394 hypoxanthine-guanine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.968 |
Clos_0534 | Clos_1590 | Clos_0534 | Clos_1590 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.742 |
Clos_0534 | Clos_1591 | Clos_0534 | Clos_1591 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.742 |
Clos_0534 | Clos_2015 | Clos_0534 | Clos_2015 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | KEGG: cdf:CD3231 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.968 |
Clos_0534 | ade | Clos_0534 | Clos_0372 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | KEGG: amt:Amet_4574 adenine deaminase; TIGRFAM: adenine deaminase; PFAM: amidohydrolase; Amidohydrolase 3; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.475 |
Clos_0534 | adk | Clos_0534 | Clos_0513 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.717 |
Clos_0534 | apt | Clos_0534 | Clos_1715 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.994 |
Clos_0534 | gmk | Clos_0534 | Clos_1423 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.979 |
Clos_0534 | purH | Clos_0534 | Clos_0541 | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | KEGG: cth:Cthe_1246 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.949 |
Clos_0920 | Clos_0534 | Clos_0920 | Clos_0534 | 5'-Nucleotidase domain protein; PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bcl:ABC0966 nucleotidase; Belongs to the 5'-nucleotidase family. | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | 0.965 |
Clos_0920 | Clos_1353 | Clos_0920 | Clos_1353 | 5'-Nucleotidase domain protein; PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bcl:ABC0966 nucleotidase; Belongs to the 5'-nucleotidase family. | KEGG: tte:TTE2394 hypoxanthine-guanine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.908 |
Clos_0920 | Clos_1590 | Clos_0920 | Clos_1590 | 5'-Nucleotidase domain protein; PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bcl:ABC0966 nucleotidase; Belongs to the 5'-nucleotidase family. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.916 |
Clos_0920 | Clos_1591 | Clos_0920 | Clos_1591 | 5'-Nucleotidase domain protein; PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bcl:ABC0966 nucleotidase; Belongs to the 5'-nucleotidase family. | Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.916 |
Clos_0920 | Clos_2015 | Clos_0920 | Clos_2015 | 5'-Nucleotidase domain protein; PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bcl:ABC0966 nucleotidase; Belongs to the 5'-nucleotidase family. | KEGG: cdf:CD3231 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.908 |
Clos_0920 | adk | Clos_0920 | Clos_0513 | 5'-Nucleotidase domain protein; PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bcl:ABC0966 nucleotidase; Belongs to the 5'-nucleotidase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.927 |
Clos_0920 | apt | Clos_0920 | Clos_1715 | 5'-Nucleotidase domain protein; PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bcl:ABC0966 nucleotidase; Belongs to the 5'-nucleotidase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.920 |
Clos_0920 | gmk | Clos_0920 | Clos_1423 | 5'-Nucleotidase domain protein; PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bcl:ABC0966 nucleotidase; Belongs to the 5'-nucleotidase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.916 |
Clos_0920 | purH | Clos_0920 | Clos_0541 | 5'-Nucleotidase domain protein; PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bcl:ABC0966 nucleotidase; Belongs to the 5'-nucleotidase family. | KEGG: cth:Cthe_1246 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.910 |
Clos_1353 | Clos_0534 | Clos_1353 | Clos_0534 | KEGG: tte:TTE2394 hypoxanthine-guanine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein. | 0.968 |