node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clos_1716 | polA | Clos_1716 | Clos_1206 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: cac:CAC2232 SsDNA exonuclease, RecJ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.644 |
Clos_1716 | queA | Clos_1716 | Clos_1723 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: cac:CAC2232 SsDNA exonuclease, RecJ. | S-adenosylmethionine--tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.414 |
Clos_1716 | recX | Clos_1716 | Clos_1601 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: cac:CAC2232 SsDNA exonuclease, RecJ. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.525 |
Clos_1716 | ruvA | Clos_1716 | Clos_1726 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: cac:CAC2232 SsDNA exonuclease, RecJ. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.515 |
Clos_1716 | ruvB | Clos_1716 | Clos_1725 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: cac:CAC2232 SsDNA exonuclease, RecJ. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.549 |
Clos_1716 | ruvC | Clos_1716 | Clos_1727 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: cac:CAC2232 SsDNA exonuclease, RecJ. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.510 |
Clos_1721 | Clos_1724 | Clos_1721 | Clos_1724 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: cdf:CD2801 putative protein translocase subunit. | TIGRFAM: SpoIID/LytB domain; PFAM: Stage II sporulation D domain protein; KEGG: cth:Cthe_0960 SpoIID/LytB domain containing protein. | 0.567 |
Clos_1721 | polA | Clos_1721 | Clos_1206 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: cdf:CD2801 putative protein translocase subunit. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.655 |
Clos_1721 | queA | Clos_1721 | Clos_1723 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: cdf:CD2801 putative protein translocase subunit. | S-adenosylmethionine--tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.815 |
Clos_1721 | ruvA | Clos_1721 | Clos_1726 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: cdf:CD2801 putative protein translocase subunit. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.672 |
Clos_1721 | ruvB | Clos_1721 | Clos_1725 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: cdf:CD2801 putative protein translocase subunit. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.682 |
Clos_1721 | ruvC | Clos_1721 | Clos_1727 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: cdf:CD2801 putative protein translocase subunit. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.570 |
Clos_1721 | tgt | Clos_1721 | Clos_1722 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: cdf:CD2801 putative protein translocase subunit. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.849 |
Clos_1724 | Clos_1721 | Clos_1724 | Clos_1721 | TIGRFAM: SpoIID/LytB domain; PFAM: Stage II sporulation D domain protein; KEGG: cth:Cthe_0960 SpoIID/LytB domain containing protein. | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: cdf:CD2801 putative protein translocase subunit. | 0.567 |
Clos_1724 | queA | Clos_1724 | Clos_1723 | TIGRFAM: SpoIID/LytB domain; PFAM: Stage II sporulation D domain protein; KEGG: cth:Cthe_0960 SpoIID/LytB domain containing protein. | S-adenosylmethionine--tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.873 |
Clos_1724 | ruvA | Clos_1724 | Clos_1726 | TIGRFAM: SpoIID/LytB domain; PFAM: Stage II sporulation D domain protein; KEGG: cth:Cthe_0960 SpoIID/LytB domain containing protein. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.575 |
Clos_1724 | ruvB | Clos_1724 | Clos_1725 | TIGRFAM: SpoIID/LytB domain; PFAM: Stage II sporulation D domain protein; KEGG: cth:Cthe_0960 SpoIID/LytB domain containing protein. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.673 |
Clos_1724 | ruvC | Clos_1724 | Clos_1727 | TIGRFAM: SpoIID/LytB domain; PFAM: Stage II sporulation D domain protein; KEGG: cth:Cthe_0960 SpoIID/LytB domain containing protein. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.556 |
Clos_1724 | tgt | Clos_1724 | Clos_1722 | TIGRFAM: SpoIID/LytB domain; PFAM: Stage II sporulation D domain protein; KEGG: cth:Cthe_0960 SpoIID/LytB domain containing protein. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.847 |
Clos_1778 | polA | Clos_1778 | Clos_1206 | PFAM: protein of unknown function DUF28; KEGG: cdf:CD0795 hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.463 |