node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LRC271 | LRC272 | LRC271 | LRC272 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Conserved hypothetical protein. | 0.822 |
LRC271 | LRC275 | LRC271 | LRC275 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Conserved hypothetical protein. | 0.968 |
LRC271 | RCIX415 | LRC271 | RCIX415 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Putative archaeosine tRNA-ribosyltransferase. | 0.753 |
LRC271 | RCIX625 | LRC271 | RCIX625 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.651 |
LRC271 | nac | LRC271 | RCIX1024 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Putative transcription factor (alpha-NAC related); Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. | 0.702 |
LRC271 | nadR | LRC271 | RCIX2287 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Nicotinamide-nucleotide adenylyltransferase. | 0.691 |
LRC271 | pfdB | LRC271 | RCIX2129 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Chaperonin cofactor prefoldin, beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.702 |
LRC271 | ribK | LRC271 | RCIX631 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Conserved hypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.696 |
LRC271 | tfeA | LRC271 | LRC274 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...] | 0.753 |
LRC271 | tiaS | LRC271 | RCIX1429 | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Conserved hypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.681 |
LRC272 | LRC271 | LRC272 | LRC271 | Conserved hypothetical protein. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.822 |
LRC272 | LRC275 | LRC272 | LRC275 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.622 |
LRC272 | tfeA | LRC272 | LRC274 | Conserved hypothetical protein. | Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...] | 0.622 |
LRC275 | LRC271 | LRC275 | LRC271 | Conserved hypothetical protein. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.968 |
LRC275 | LRC272 | LRC275 | LRC272 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.622 |
LRC275 | RCIX415 | LRC275 | RCIX415 | Conserved hypothetical protein. | Putative archaeosine tRNA-ribosyltransferase. | 0.413 |
LRC275 | tfeA | LRC275 | LRC274 | Conserved hypothetical protein. | Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...] | 0.822 |
RCIX415 | LRC271 | RCIX415 | LRC271 | Putative archaeosine tRNA-ribosyltransferase. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.753 |
RCIX415 | LRC275 | RCIX415 | LRC275 | Putative archaeosine tRNA-ribosyltransferase. | Conserved hypothetical protein. | 0.413 |
RCIX415 | RCIX625 | RCIX415 | RCIX625 | Putative archaeosine tRNA-ribosyltransferase. | Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.677 |