STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B8BQU1_THAPSUncharacterized protein. (558 aa)    
Predicted Functional Partners:
B8CDE4_THAPS
Chromatin assembly factor.
   
 0.963
H4_2
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.961
B8C0N6_THAPS
Uncharacterized protein.
    
 
 0.831
ORC2
ORC2, origin recognition complex subunit 2.
   
 
 0.828
THAPS_35372
Predicted protein.
   
 
 0.805
B8CA51_THAPS
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
 
 0.738
H3-2
Histone H3; Belongs to the histone H3 family.
   
 
 0.645
H3
Histone H3.
    
 
 0.644
B8BXC5_THAPS
DUF2236 domain-containing protein.
    
 
 0.644
B8CC53_THAPS
Histone H3; Belongs to the histone H3 family.
    
 
 0.644
Your Current Organism:
Thalassiosira pseudonana
NCBI taxonomy Id: 35128
Other names: T. pseudonana
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.