node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Maqu_0882 | Maqu_0883 | Maqu_0882 | Maqu_0883 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_05916 acetolactate synthase, large subunit, biosynthetic type. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: hch:HCH_05915 acetolactate synthase, small subunit. | 0.999 |
Maqu_0882 | Maqu_2114 | Maqu_0882 | Maqu_2114 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_05916 acetolactate synthase, large subunit, biosynthetic type. | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_06858 acetolactate synthase, large subunit, biosynthetic type. | 0.909 |
Maqu_0882 | Maqu_2115 | Maqu_0882 | Maqu_2115 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_05916 acetolactate synthase, large subunit, biosynthetic type. | KEGG: hch:HCH_06859 acetolactate synthase (isozyme II), small (regulatory) subunit. | 0.926 |
Maqu_0882 | Maqu_2345 | Maqu_0882 | Maqu_2345 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_05916 acetolactate synthase, large subunit, biosynthetic type. | PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: mle:ML0354 acetolactate synthase large subunit. | 0.917 |
Maqu_0882 | Maqu_3397 | Maqu_0882 | Maqu_3397 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_05916 acetolactate synthase, large subunit, biosynthetic type. | PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_02178 thiamine pyrophosphate-requiring enzyme; Belongs to the TPP enzyme family. | 0.922 |
Maqu_0882 | ilvC | Maqu_0882 | Maqu_0884 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_05916 acetolactate synthase, large subunit, biosynthetic type. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.996 |
Maqu_0882 | ilvD | Maqu_0882 | Maqu_2116 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_05916 acetolactate synthase, large subunit, biosynthetic type. | KEGG: abo:ABO_0180 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.895 |
Maqu_0882 | ilvD-2 | Maqu_0882 | Maqu_2423 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_05916 acetolactate synthase, large subunit, biosynthetic type. | KEGG: pst:PSPTO_5057 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.828 |
Maqu_0882 | leuB | Maqu_0882 | Maqu_1563 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_05916 acetolactate synthase, large subunit, biosynthetic type. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.976 |
Maqu_0882 | leuC | Maqu_0882 | Maqu_1565 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_05916 acetolactate synthase, large subunit, biosynthetic type. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.646 |
Maqu_0883 | Maqu_0882 | Maqu_0883 | Maqu_0882 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: hch:HCH_05915 acetolactate synthase, small subunit. | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_05916 acetolactate synthase, large subunit, biosynthetic type. | 0.999 |
Maqu_0883 | Maqu_2114 | Maqu_0883 | Maqu_2114 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: hch:HCH_05915 acetolactate synthase, small subunit. | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_06858 acetolactate synthase, large subunit, biosynthetic type. | 0.998 |
Maqu_0883 | Maqu_2115 | Maqu_0883 | Maqu_2115 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: hch:HCH_05915 acetolactate synthase, small subunit. | KEGG: hch:HCH_06859 acetolactate synthase (isozyme II), small (regulatory) subunit. | 0.914 |
Maqu_0883 | Maqu_2345 | Maqu_0883 | Maqu_2345 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: hch:HCH_05915 acetolactate synthase, small subunit. | PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: mle:ML0354 acetolactate synthase large subunit. | 0.992 |
Maqu_0883 | Maqu_3397 | Maqu_0883 | Maqu_3397 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: hch:HCH_05915 acetolactate synthase, small subunit. | PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: hch:HCH_02178 thiamine pyrophosphate-requiring enzyme; Belongs to the TPP enzyme family. | 0.993 |
Maqu_0883 | ilvC | Maqu_0883 | Maqu_0884 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: hch:HCH_05915 acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
Maqu_0883 | ilvD | Maqu_0883 | Maqu_2116 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: hch:HCH_05915 acetolactate synthase, small subunit. | KEGG: abo:ABO_0180 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.789 |
Maqu_0883 | ilvD-2 | Maqu_0883 | Maqu_2423 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: hch:HCH_05915 acetolactate synthase, small subunit. | KEGG: pst:PSPTO_5057 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.726 |
Maqu_0883 | leuB | Maqu_0883 | Maqu_1563 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: hch:HCH_05915 acetolactate synthase, small subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.985 |
Maqu_0883 | leuC | Maqu_0883 | Maqu_1565 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: hch:HCH_05915 acetolactate synthase, small subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.898 |