node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apt | guaA | Maqu_2814 | Maqu_1727 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.993 |
apt | guaB | Maqu_2814 | Maqu_1728 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.522 |
apt | map | Maqu_2814 | Maqu_2549 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.426 |
apt | purL | Maqu_2814 | Maqu_2484 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.841 |
apt | pyrG | Maqu_2814 | Maqu_0919 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.532 |
argS | guaA | Maqu_0820 | Maqu_1727 | KEGG: csa:Csal_0602 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.999 |
argS | lysS | Maqu_0820 | Maqu_2270 | KEGG: csa:Csal_0602 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase, class II (D, K and N); nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: abo:ABO_1648 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.919 |
argS | purL | Maqu_0820 | Maqu_2484 | KEGG: csa:Csal_0602 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.686 |
argS | pyrG | Maqu_0820 | Maqu_0919 | KEGG: csa:Csal_0602 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.855 |
argS | rplA | Maqu_0820 | Maqu_0709 | KEGG: csa:Csal_0602 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.574 |
argS | rplK | Maqu_0820 | Maqu_0708 | KEGG: csa:Csal_0602 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.613 |
argS | tuf | Maqu_0820 | Maqu_0717 | KEGG: csa:Csal_0602 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.460 |
guaA | apt | Maqu_1727 | Maqu_2814 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.993 |
guaA | argS | Maqu_1727 | Maqu_0820 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | KEGG: csa:Csal_0602 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. | 0.999 |
guaA | guaB | Maqu_1727 | Maqu_1728 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | lysS | Maqu_1727 | Maqu_2270 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase, class II (D, K and N); nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: abo:ABO_1648 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.979 |
guaA | map | Maqu_1727 | Maqu_2549 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.986 |
guaA | purL | Maqu_1727 | Maqu_2484 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.996 |
guaA | pyrG | Maqu_1727 | Maqu_0919 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.986 |
guaA | rplA | Maqu_1727 | Maqu_0709 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.978 |