node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Maqu_0486 | Maqu_1546 | Maqu_0486 | Maqu_1546 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: hch:HCH_02450 uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.941 |
Maqu_0486 | Maqu_3131 | Maqu_0486 | Maqu_3131 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pen:PSEEN2217 siroheme synthase; Belongs to the precorrin methyltransferase family. | 0.939 |
Maqu_0486 | Maqu_3578 | Maqu_0486 | Maqu_3578 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pen:PSEEN5337 delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Belongs to the ALAD family. | 0.901 |
Maqu_0486 | hemA | Maqu_0486 | Maqu_2361 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.749 |
Maqu_0486 | hemC | Maqu_0486 | Maqu_0487 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
Maqu_0486 | hemL | Maqu_0486 | Maqu_0686 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: hch:HCH_06248 glutamate-1-semialdehyde-2,1-aminomutase. | 0.600 |
Maqu_1546 | Maqu_0486 | Maqu_1546 | Maqu_0486 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: hch:HCH_02450 uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.941 |
Maqu_1546 | Maqu_3131 | Maqu_1546 | Maqu_3131 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: hch:HCH_02450 uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pen:PSEEN2217 siroheme synthase; Belongs to the precorrin methyltransferase family. | 0.905 |
Maqu_1546 | Maqu_3578 | Maqu_1546 | Maqu_3578 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: hch:HCH_02450 uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pen:PSEEN5337 delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Belongs to the ALAD family. | 0.868 |
Maqu_1546 | hemA | Maqu_1546 | Maqu_2361 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: hch:HCH_02450 uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.768 |
Maqu_1546 | hemC | Maqu_1546 | Maqu_0487 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: hch:HCH_02450 uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.988 |
Maqu_1546 | hemL | Maqu_1546 | Maqu_0686 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: hch:HCH_02450 uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: hch:HCH_06248 glutamate-1-semialdehyde-2,1-aminomutase. | 0.712 |
Maqu_2358 | hemA | Maqu_2358 | Maqu_2361 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: pfo:Pfl_4746 UBA/ThiF-type NAD/FAD binding fold. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.795 |
Maqu_2358 | prfA | Maqu_2358 | Maqu_2360 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: pfo:Pfl_4746 UBA/ThiF-type NAD/FAD binding fold. | Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.794 |
Maqu_2358 | prmC | Maqu_2358 | Maqu_2359 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: pfo:Pfl_4746 UBA/ThiF-type NAD/FAD binding fold. | [protein release factor]-glutamine N5-methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.789 |
Maqu_3131 | Maqu_0486 | Maqu_3131 | Maqu_0486 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pen:PSEEN2217 siroheme synthase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.939 |
Maqu_3131 | Maqu_1546 | Maqu_3131 | Maqu_1546 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pen:PSEEN2217 siroheme synthase; Belongs to the precorrin methyltransferase family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: hch:HCH_02450 uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.905 |
Maqu_3131 | Maqu_3578 | Maqu_3131 | Maqu_3578 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pen:PSEEN2217 siroheme synthase; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pen:PSEEN5337 delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Belongs to the ALAD family. | 0.868 |
Maqu_3131 | hemA | Maqu_3131 | Maqu_2361 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pen:PSEEN2217 siroheme synthase; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.772 |
Maqu_3131 | hemC | Maqu_3131 | Maqu_0487 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pen:PSEEN2217 siroheme synthase; Belongs to the precorrin methyltransferase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.988 |