STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (216 aa)    
Predicted Functional Partners:
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 0.988
Maqu_2083
PFAM: CinA domain protein; KEGG: yps:YPTB0822 putative competence-damaged protein; Belongs to the CinA family.
 
 
 0.964
nadE
DNA-directed RNA polymerase, subunit H; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.955
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.954
Maqu_0952
KEGG: pfl:PFL_0851 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
    
 0.939
Maqu_2237
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: hch:HCH_01808 predicted pyrophosphatase.
    
 0.927
surE
3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.921
cobB
PFAM: Silent information regulator protein Sir2; KEGG: hch:HCH_00109 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.
   
 0.917
Maqu_3751
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: tbd:Tbd_0839 HAD-superfamily hydrolase subfamily IA, variant 3.
    
 0.917
Maqu_2227
PFAM: NUDIX hydrolase; KEGG: pau:PA14_40950 putative NADH pyrophosphatase; Belongs to the Nudix hydrolase family.
     
 0.906
Your Current Organism:
Marinobacter hydrocarbonoclasticus
NCBI taxonomy Id: 351348
Other names: M. hydrocarbonoclasticus VT8, Marinobacter aquaeolei VT8, Marinobacter aquaeolei str. VT8, Marinobacter aquaeolei strain VT8, Marinobacter hydrocarbonoclasticus VT8
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