node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Maqu_1334 | dapE | Maqu_1334 | Maqu_2554 | 23S rRNA m(1)G-745 methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: tbd:Tbd_1059 rRNA (guanine-N1-)-methyltransferase, putative. | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.564 |
Maqu_2551 | Maqu_2552 | Maqu_2551 | Maqu_2552 | PFAM: aminotransferase, class I and II; KEGG: pae:PA3659 N-succinyldiaminopimelate aminotransferase. | PFAM: arsenate reductase and related; KEGG: sal:Sala_2210 hypothetical protein; Belongs to the ArsC family. | 0.799 |
Maqu_2551 | dapD | Maqu_2551 | Maqu_2553 | PFAM: aminotransferase, class I and II; KEGG: pae:PA3659 N-succinyldiaminopimelate aminotransferase. | Tetrahydrodipicolinate succinylase, putative; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.969 |
Maqu_2551 | dapE | Maqu_2551 | Maqu_2554 | PFAM: aminotransferase, class I and II; KEGG: pae:PA3659 N-succinyldiaminopimelate aminotransferase. | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.963 |
Maqu_2551 | glnD | Maqu_2551 | Maqu_2550 | PFAM: aminotransferase, class I and II; KEGG: pae:PA3659 N-succinyldiaminopimelate aminotransferase. | Metal dependent phosphohydrolase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. | 0.799 |
Maqu_2551 | map | Maqu_2551 | Maqu_2549 | PFAM: aminotransferase, class I and II; KEGG: pae:PA3659 N-succinyldiaminopimelate aminotransferase. | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.816 |
Maqu_2552 | Maqu_2551 | Maqu_2552 | Maqu_2551 | PFAM: arsenate reductase and related; KEGG: sal:Sala_2210 hypothetical protein; Belongs to the ArsC family. | PFAM: aminotransferase, class I and II; KEGG: pae:PA3659 N-succinyldiaminopimelate aminotransferase. | 0.799 |
Maqu_2552 | dapD | Maqu_2552 | Maqu_2553 | PFAM: arsenate reductase and related; KEGG: sal:Sala_2210 hypothetical protein; Belongs to the ArsC family. | Tetrahydrodipicolinate succinylase, putative; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.701 |
Maqu_2552 | dapE | Maqu_2552 | Maqu_2554 | PFAM: arsenate reductase and related; KEGG: sal:Sala_2210 hypothetical protein; Belongs to the ArsC family. | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.865 |
Maqu_2552 | glnD | Maqu_2552 | Maqu_2550 | PFAM: arsenate reductase and related; KEGG: sal:Sala_2210 hypothetical protein; Belongs to the ArsC family. | Metal dependent phosphohydrolase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. | 0.799 |
Maqu_2552 | map | Maqu_2552 | Maqu_2549 | PFAM: arsenate reductase and related; KEGG: sal:Sala_2210 hypothetical protein; Belongs to the ArsC family. | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.799 |
argA | dapB | Maqu_3557 | Maqu_3360 | N-acetylglutamate synthase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: ppu:PP_5185 N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.563 |
argA | dapE | Maqu_3557 | Maqu_2554 | N-acetylglutamate synthase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: ppu:PP_5185 N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.591 |
argA | dapF | Maqu_3557 | Maqu_0495 | N-acetylglutamate synthase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: ppu:PP_5185 N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.588 |
dapB | argA | Maqu_3360 | Maqu_3557 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | N-acetylglutamate synthase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: ppu:PP_5185 N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | 0.563 |
dapB | dapD | Maqu_3360 | Maqu_2553 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Tetrahydrodipicolinate succinylase, putative; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.961 |
dapB | dapE | Maqu_3360 | Maqu_2554 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.523 |
dapB | dapF | Maqu_3360 | Maqu_0495 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.777 |
dapD | Maqu_2551 | Maqu_2553 | Maqu_2551 | Tetrahydrodipicolinate succinylase, putative; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | PFAM: aminotransferase, class I and II; KEGG: pae:PA3659 N-succinyldiaminopimelate aminotransferase. | 0.969 |
dapD | Maqu_2552 | Maqu_2553 | Maqu_2552 | Tetrahydrodipicolinate succinylase, putative; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | PFAM: arsenate reductase and related; KEGG: sal:Sala_2210 hypothetical protein; Belongs to the ArsC family. | 0.701 |