node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Maqu_1795 | dnaK | Maqu_1795 | Maqu_3362 | PFAM: heat shock protein DnaJ domain protein; KEGG: pae:PA1191 hypothetical protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.934 |
Maqu_1795 | groL | Maqu_1795 | Maqu_2030 | PFAM: heat shock protein DnaJ domain protein; KEGG: pae:PA1191 hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.740 |
Maqu_1795 | groS | Maqu_1795 | Maqu_2031 | PFAM: heat shock protein DnaJ domain protein; KEGG: pae:PA1191 hypothetical protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.545 |
Maqu_1795 | grpE | Maqu_1795 | Maqu_3363 | PFAM: heat shock protein DnaJ domain protein; KEGG: pae:PA1191 hypothetical protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.810 |
Maqu_1795 | htpG | Maqu_1795 | Maqu_1054 | PFAM: heat shock protein DnaJ domain protein; KEGG: pae:PA1191 hypothetical protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.837 |
Maqu_1795 | rplP | Maqu_1795 | Maqu_0726 | PFAM: heat shock protein DnaJ domain protein; KEGG: pae:PA1191 hypothetical protein. | LSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.438 |
Maqu_2298 | djlA | Maqu_2298 | Maqu_2106 | PFAM: heat shock protein DnaJ domain protein; KEGG: csa:Csal_0951 heat shock protein DnaJ-like protein. | Heat shock protein DnaJ domain protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 0.664 |
Maqu_2298 | dnaK | Maqu_2298 | Maqu_3362 | PFAM: heat shock protein DnaJ domain protein; KEGG: csa:Csal_0951 heat shock protein DnaJ-like protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.934 |
Maqu_2298 | groL | Maqu_2298 | Maqu_2030 | PFAM: heat shock protein DnaJ domain protein; KEGG: csa:Csal_0951 heat shock protein DnaJ-like protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.740 |
Maqu_2298 | groS | Maqu_2298 | Maqu_2031 | PFAM: heat shock protein DnaJ domain protein; KEGG: csa:Csal_0951 heat shock protein DnaJ-like protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.545 |
Maqu_2298 | grpE | Maqu_2298 | Maqu_3363 | PFAM: heat shock protein DnaJ domain protein; KEGG: csa:Csal_0951 heat shock protein DnaJ-like protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.810 |
Maqu_2298 | htpG | Maqu_2298 | Maqu_1054 | PFAM: heat shock protein DnaJ domain protein; KEGG: csa:Csal_0951 heat shock protein DnaJ-like protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.837 |
Maqu_2298 | rplP | Maqu_2298 | Maqu_0726 | PFAM: heat shock protein DnaJ domain protein; KEGG: csa:Csal_0951 heat shock protein DnaJ-like protein. | LSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.438 |
Maqu_3023 | dnaK | Maqu_3023 | Maqu_3362 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: hch:HCH_00524 DnaJ-class molecular chaperone. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.989 |
Maqu_3023 | groL | Maqu_3023 | Maqu_2030 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: hch:HCH_00524 DnaJ-class molecular chaperone. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.798 |
Maqu_3023 | groS | Maqu_3023 | Maqu_2031 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: hch:HCH_00524 DnaJ-class molecular chaperone. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.667 |
Maqu_3023 | grpE | Maqu_3023 | Maqu_3363 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: hch:HCH_00524 DnaJ-class molecular chaperone. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.944 |
Maqu_3023 | htpG | Maqu_3023 | Maqu_1054 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: hch:HCH_00524 DnaJ-class molecular chaperone. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.837 |
Maqu_3023 | rplP | Maqu_3023 | Maqu_0726 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: hch:HCH_00524 DnaJ-class molecular chaperone. | LSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.438 |
djlA | Maqu_2298 | Maqu_2106 | Maqu_2298 | Heat shock protein DnaJ domain protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | PFAM: heat shock protein DnaJ domain protein; KEGG: csa:Csal_0951 heat shock protein DnaJ-like protein. | 0.664 |