STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Maqu_3741PFAM: Xylose isomerase domain protein TIM barrel; KEGG: abo:ABO_1233 hydroxypyruvate isomerase; Belongs to the hyi family. (259 aa)    
Predicted Functional Partners:
Maqu_3054
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: hch:HCH_01519 lactate dehydrogenase and related dehydrogenase.
   
 
 0.906
Maqu_3742
PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: abo:ABO_1232 2-hydroxy-3-oxopropionate reductase.
  
 0.875
Maqu_3739
Signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: hch:HCH_00580 signal transduction histidine kinase.
       0.523
Maqu_3740
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: hch:HCH_00579 response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
       0.523
Maqu_1147
PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: bxe:Bxe_B0704 putative 3-hydroxyisobutyrate dehydrogenase.
  
 0.462
Maqu_1164
PFAM: regulatory protein GntR, HTH; KEGG: hch:HCH_04733 transcriptional regulator.
  
     0.417
Maqu_2129
KEGG: pae:PA3569 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; Belongs to the HIBADH-related family.
  
 0.415
rpoH
RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
       0.401
Your Current Organism:
Marinobacter hydrocarbonoclasticus
NCBI taxonomy Id: 351348
Other names: M. hydrocarbonoclasticus VT8, Marinobacter aquaeolei VT8, Marinobacter aquaeolei str. VT8, Marinobacter aquaeolei strain VT8, Marinobacter hydrocarbonoclasticus VT8
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.