node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gura_1188 | ruvC | Gura_1188 | Gura_1415 | PFAM: protein of unknown function DUF559. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.682 |
Gura_1220 | ligA | Gura_1220 | Gura_1305 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.668 |
Gura_1220 | polA | Gura_1220 | Gura_3902 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.967 |
Gura_1220 | recX | Gura_1220 | Gura_0221 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.586 |
Gura_1220 | ruvA | Gura_1220 | Gura_1414 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.571 |
Gura_1220 | ruvB | Gura_1220 | Gura_1413 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.594 |
Gura_1220 | ruvC | Gura_1220 | Gura_1415 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.645 |
Gura_1412 | Gura_1416 | Gura_1412 | Gura_1416 | Regulatory inactivation of DnaA Hda protein; PFAM: Chromosomal replication initiator, DnaA; Belongs to the DnaA family. | PFAM: protein of unknown function DUF28. | 0.469 |
Gura_1412 | ruvA | Gura_1412 | Gura_1414 | Regulatory inactivation of DnaA Hda protein; PFAM: Chromosomal replication initiator, DnaA; Belongs to the DnaA family. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.708 |
Gura_1412 | ruvB | Gura_1412 | Gura_1413 | Regulatory inactivation of DnaA Hda protein; PFAM: Chromosomal replication initiator, DnaA; Belongs to the DnaA family. | Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.878 |
Gura_1412 | ruvC | Gura_1412 | Gura_1415 | Regulatory inactivation of DnaA Hda protein; PFAM: Chromosomal replication initiator, DnaA; Belongs to the DnaA family. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.586 |
Gura_1416 | Gura_1412 | Gura_1416 | Gura_1412 | PFAM: protein of unknown function DUF28. | Regulatory inactivation of DnaA Hda protein; PFAM: Chromosomal replication initiator, DnaA; Belongs to the DnaA family. | 0.469 |
Gura_1416 | ruvA | Gura_1416 | Gura_1414 | PFAM: protein of unknown function DUF28. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.717 |
Gura_1416 | ruvB | Gura_1416 | Gura_1413 | PFAM: protein of unknown function DUF28. | Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.705 |
Gura_1416 | ruvC | Gura_1416 | Gura_1415 | PFAM: protein of unknown function DUF28. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.759 |
Gura_4031 | ruvC | Gura_4031 | Gura_1415 | TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.614 |
ligA | Gura_1220 | Gura_1305 | Gura_1220 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.668 |
ligA | polA | Gura_1305 | Gura_3902 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.758 |
ligA | ruvA | Gura_1305 | Gura_1414 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.471 |
ligA | ruvB | Gura_1305 | Gura_1413 | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.661 |