STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cgd2_2060General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (709 aa)    
Predicted Functional Partners:
cgd6_5040
Transcription factor, putative.
   
 0.999
cgd1_3300
Ring domain protein.
    
 0.999
cgd3_3110
Transcription factor TFIIH with a vWA domain.
   
 0.999
cgd8_1940
RAD25, helicase involved in DNA repair.
  
 0.999
cgd7_820
RAD3'DEXDc+HELICc protein.
    
 0.999
cgd4_3810
Putative transcription factor IIE alpha subunit.
   
 0.998
cgd5_1030
Apicomplexan conserved protein.
    
 0.993
cgd1_3310
Cyclin domain protein, possible cyclin H; Belongs to the cyclin family.
    
 0.991
cgd8_880
Transcription initiation factor TFIIB Sua7p ZnR+2cyclins.
    
 0.991
cgd7_430
Cyclin-dependent kinase-related kinase, putative; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.980
Your Current Organism:
Cryptosporidium parvum
NCBI taxonomy Id: 353152
Other names: C. parvum Iowa II, Cryptosporidium parvum Iowa II, Cryptosporidium parvum strain Iowa type II
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.