STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABQ89975.1PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase. (552 aa)    
Predicted Functional Partners:
ABQ89974.1
Exonuclease of the beta-lactamase fold involved in RNA processing-like protein.
 0.995
ABQ92739.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.989
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.976
ABQ88517.1
PFAM: helix-hairpin-helix motif; PHP C-terminal domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; Helix-hairpin-helix DNA-binding, class 1.
  
 0.934
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
    
 0.930
ABQ89075.1
PFAM: Endonuclease/exonuclease/phosphatase.
 
 
 0.891
ABQ91907.1
ICC-like phosphoesterase-like protein.
 
   
 0.827
ABQ89976.1
PFAM: histone deacetylase superfamily.
 
    0.816
ABQ91788.1
PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like.
 
    0.804
dinG
DNA polymerase III, epsilon subunit; 3'-5' exonuclease.
   
 
 0.792
Your Current Organism:
Roseiflexus sp. RS1
NCBI taxonomy Id: 357808
Other names: R. sp. RS-1, Roseiflexus sp. RS-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.