STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cphy_1362PFAM: protein of unknown function DUF214; KEGG: lmf:LMOf2365_1233 ABC transporter, permease protein. (1090 aa)    
Predicted Functional Partners:
Cphy_1363
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cac:CAC0822 ABC transporter, ATP-binding protein.
 
  
 0.959
Cphy_2590
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cac:CAC0822 ABC transporter, ATP-binding protein.
 
  
 0.829
Cphy_1857
PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: blo:BL1369 large protein with N-terminal similarity to ATP binding protein of ABC transporter.
 
  
 0.752
Cphy_2202
PFAM: phosphopantetheine-binding; KEGG: ckl:CKL_1730 polyketide synthase-related protein.
  
  
 0.651
Cphy_1364
PFAM: regulatory protein TetR; KEGG: cbe:Cbei_3107 transcriptional regulator, TetR family.
 
    0.590
Cphy_0192
PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: ppe:PEPE_1650 ABC-type antimicrobial peptide transport system, ATPase component.
  
  
 0.552
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.549
Cphy_2079
PFAM: protein of unknown function DUF214; KEGG: cth:Cthe_0540 protein of unknown function DUF214.
  
 
 0.533
Cphy_2589
PFAM: protein of unknown function DUF214; KEGG: efa:EF1321 permease domain protein.
 
  
0.527
Cphy_1345
PFAM: prephenate dehydratase; Chorismate mutase; KEGG: ckl:CKL_0789 PheA.
  
  
 0.513
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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