STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfk6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.996
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.986
pgi-2
Putative glucose-6-phosphate isomerase.
  
 0.982
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.966
BAH46789.1
Probable fructose/tagatose bisphosphate aldolase.
 
 
 0.953
fba
Fructose-1,6-bisphosphate aldolase.
 
 
 0.952
tktA
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.942
fruB
Fructose 1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
  
 0.942
tal
Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.938
mtlD
Mannitol-1-phosphate 5-dehydrogenase.
 
  
 0.934
Your Current Organism:
Brevibacillus brevis
NCBI taxonomy Id: 358681
Other names: B. brevis NBRC 100599, Brevibacillus brevis NBRC 100599, Brevibacillus brevis str. NBRC 100599, Brevibacillus brevis strain NBRC 100599
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