STRINGSTRING
pnp protein (Brevibacillus brevis) - STRING interaction network
"pnp" - Polyribonucleotide nucleotidyltransferase in Brevibacillus brevis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’- to 5’-direction (715 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1179 aa)
   
  0.973
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (314 aa)
   
  0.970
rpoC
DNA-directed RNA polymerase beta’ chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1208 aa)
 
 
  0.961
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (876 aa)
 
 
  0.960
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (147 aa)
   
 
  0.959
eno
Enolase; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (428 aa)
   
 
  0.949
cafA
Ribonuclease G (491 aa)
   
  0.946
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (214 aa)
   
 
  0.943
pyk
Pyruvate kinase (584 aa)
   
 
  0.942
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP (240 aa)
   
 
  0.934
Your Current Organism:
Brevibacillus brevis
NCBI taxonomy Id: 358681
Other names: B. brevis, B. brevis NBRC 100599, Bacillus brevis, Brevibacillus brevis, Brevibacillus brevis NBRC 100599, Brevibacillus brevis str. NBRC 100599, Brevibacillus brevis strain NBRC 100599
Server load: low (8%) [HD]