node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAH43181.1 | megL | BBR47_22040 | BBR47_55420 | Putative 5,10-methylenetetrahydrofolate reductase. | Probable methionine gamma-lyase. | 0.989 |
BAH43181.1 | metE | BBR47_22040 | BBR47_31330 | Putative 5,10-methylenetetrahydrofolate reductase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.998 |
BAH43181.1 | metH | BBR47_22040 | BBR47_22030 | Putative 5,10-methylenetetrahydrofolate reductase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
BAH43181.1 | metK | BBR47_22040 | BBR47_54050 | Putative 5,10-methylenetetrahydrofolate reductase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.990 |
BAH43181.1 | mtnE | BBR47_22040 | BBR47_41850 | Putative 5,10-methylenetetrahydrofolate reductase. | Aminotransferase MtnE. | 0.952 |
BAH43181.1 | ybgG | BBR47_22040 | BBR47_30220 | Putative 5,10-methylenetetrahydrofolate reductase. | Homocysteine S-methyltransferase. | 0.950 |
BAH43239.1 | metK | BBR47_22620 | BBR47_54050 | Probable transcriptional regulator. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.917 |
BAH43239.1 | speD | BBR47_22620 | BBR47_08050 | Probable transcriptional regulator. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.900 |
BAH43239.1 | speD-2 | BBR47_22620 | BBR47_38870 | Probable transcriptional regulator. | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.900 |
megL | BAH43181.1 | BBR47_55420 | BBR47_22040 | Probable methionine gamma-lyase. | Putative 5,10-methylenetetrahydrofolate reductase. | 0.989 |
megL | metE | BBR47_55420 | BBR47_31330 | Probable methionine gamma-lyase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.950 |
megL | metH | BBR47_55420 | BBR47_22030 | Probable methionine gamma-lyase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.972 |
megL | metK | BBR47_55420 | BBR47_54050 | Probable methionine gamma-lyase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.924 |
megL | mtnE | BBR47_55420 | BBR47_41850 | Probable methionine gamma-lyase. | Aminotransferase MtnE. | 0.917 |
megL | ybgG | BBR47_55420 | BBR47_30220 | Probable methionine gamma-lyase. | Homocysteine S-methyltransferase. | 0.921 |
metE | BAH43181.1 | BBR47_31330 | BBR47_22040 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Putative 5,10-methylenetetrahydrofolate reductase. | 0.998 |
metE | megL | BBR47_31330 | BBR47_55420 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Probable methionine gamma-lyase. | 0.950 |
metE | metH | BBR47_31330 | BBR47_22030 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.986 |
metE | metK | BBR47_31330 | BBR47_54050 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.985 |
metE | mtnE | BBR47_31330 | BBR47_41850 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Aminotransferase MtnE. | 0.913 |