STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CN09_02165MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology (424 aa)    
Predicted Functional Partners:
hflK
Hypothetical protein; HflC and HflK could encode or regulate a protease
 
 
  0.964
CN09_05390
Membrane protein; HflC and HflK could regulate a protease
 
 
  0.961
CN09_24085
Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology
 
  
 0.961
CN09_12010
Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology
   
 0.957
CN09_16790
Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology
   
 0.957
CN09_21885
Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology
   
 0.957
pepN
Aminopeptidase n; Derived by automated computational analysis using gene prediction method: Protein Homology
   
  0.956
CN09_32650
Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology
    
 0.956
dnaJ
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are require [...]
   
 0.956
CN09_00410
Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology
   
 0.955
Your Current Organism:
Agrobacterium rhizogenes
NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509
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