purA protein (Agrobacterium rhizogenes) - STRING interaction network

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purA

Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (431 aa)

Predicted Functional Partners:

guaA

0.999

nnrD

0.999

purH

0.998

CN09_06715

0.997

guaB

0.997

pheT

0.988

CN09_08270

0.980

purD

0.974

purE

0.960

prs

0.958

Your Current Organism:

Agrobacterium rhizogenes

NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CN09_06715	CN09_08270	CN09_06715	CN09_08270	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology	0.497
CN09_06715	guaA	CN09_06715	CN09_14055	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	0.997
CN09_06715	guaB	CN09_06715	CN09_16005	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family	0.976
CN09_06715	pheT	CN09_06715	CN09_13825	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	Phenylalanine--tRNA ligase beta subunit; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	0.916
CN09_06715	prs	CN09_06715	CN09_04275	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily	0.748
CN09_06715	purA	CN09_06715	CN09_02930	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family	0.997
CN09_06715	purD	CN09_06715	CN09_16590	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the GARS family	0.975
CN09_06715	purE	CN09_06715	CN09_02065	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	0.607
CN09_06715	purH	CN09_06715	CN09_17805	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	Bifunctional purine biosynthesis protein PurH; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method- Protein Homology	0.993
CN09_08270	CN09_06715	CN09_08270	CN09_06715	Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	0.497
CN09_08270	guaA	CN09_08270	CN09_14055	Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	0.999
CN09_08270	guaB	CN09_08270	CN09_16005	Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology	Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family	0.917
CN09_08270	nnrD	CN09_08270	CN09_07485	Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.999
CN09_08270	pheT	CN09_08270	CN09_13825	Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology	Phenylalanine--tRNA ligase beta subunit; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	0.999
CN09_08270	purA	CN09_08270	CN09_02930	Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family	0.980
CN09_08270	purD	CN09_08270	CN09_16590	Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology	Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the GARS family	0.404
CN09_08270	purE	CN09_08270	CN09_02065	Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology	N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	0.594
guaA	CN09_06715	CN09_14055	CN09_06715	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	0.997
guaA	CN09_08270	CN09_14055	CN09_08270	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology	0.999
guaA	guaB	CN09_14055	CN09_16005	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family	0.999

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