STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
derGtp-binding protein der; GTPase that plays an essential role in the late steps of ribosome biogenesis (475 aa)    
Predicted Functional Partners:
CN09_03745
3-hydroxybutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology
     
 0.999
CN09_03820
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology
 
     0.999
CN09_08270
Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology
     
 0.999
pheT
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
 
  
 0.999
guaB
inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
  
  
 0.999
cmk
Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytidylate kinase family. Type 1 subfamily
  
 0.958
truB
Trna pseudouridine synthase b; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs
 
  
 0.935
lepA
Gtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner
 
 
 0.934
polA
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
 
    0.931
hflX
Gtp-binding protein hflx; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
 
   
 0.930
Your Current Organism:
Agrobacterium rhizogenes
NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509
Server load: low (14%) [HD]