| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CN09_04790 | CN09_10410 | CN09_04790 | CN09_10410 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family | 0.540 |
| CN09_04790 | CN09_28065 | CN09_04790 | CN09_28065 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.491 |
| CN09_04790 | ctaB | CN09_04790 | CN09_16840 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily | 0.837 |
| CN09_04790 | hemC | CN09_04790 | CN09_28060 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps; Belongs to the HMBS family | 0.869 |
| CN09_04790 | hemE | CN09_04790 | CN09_17710 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III | 0.727 |
| CN09_04790 | hemF | CN09_04790 | CN09_04145 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate | Oxygen-dependent coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX | 0.890 |
| CN09_04790 | hemH | CN09_04790 | CN09_01880 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family | 0.859 |
| CN09_04790 | ubiG | CN09_04790 | CN09_27240 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family | 0.948 |
| CN09_10410 | CN09_04790 | CN09_10410 | CN09_04790 | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate | 0.540 |
| CN09_10410 | CN09_27710 | CN09_10410 | CN09_27710 | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family | Catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.953 |
| CN09_10410 | CN09_28065 | CN09_10410 | CN09_28065 | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.961 |
| CN09_10410 | ctaB | CN09_10410 | CN09_16840 | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily | 0.848 |
| CN09_10410 | hemC | CN09_10410 | CN09_28060 | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps; Belongs to the HMBS family | 0.992 |
| CN09_10410 | hemE | CN09_10410 | CN09_17710 | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III | 0.985 |
| CN09_10410 | hemF | CN09_10410 | CN09_04145 | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family | Oxygen-dependent coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX | 0.949 |
| CN09_10410 | hemH | CN09_10410 | CN09_01880 | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family | 0.960 |
| CN09_10410 | topA | CN09_10410 | CN09_09825 | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA super [...] | 0.914 |
| CN09_10410 | ubiG | CN09_10410 | CN09_27240 | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family | 0.813 |
| CN09_27710 | CN09_10410 | CN09_27710 | CN09_10410 | Catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; Derived by automated computational analysis using gene prediction method- Protein Homology | Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family | 0.953 |
| CN09_27710 | ctaB | CN09_27710 | CN09_16840 | Catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; Derived by automated computational analysis using gene prediction method- Protein Homology | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily | 0.833 |
